中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2014年
34期
5555-5560
,共6页
张佳%胡素琴%严璐%王桂玲
張佳%鬍素琴%嚴璐%王桂玲
장가%호소금%엄로%왕계령
生物材料%材料相容性%甲壳质医用创面贴%伤口换药%临床疗效%细菌检出率%抗菌%愈合率%敷料
生物材料%材料相容性%甲殼質醫用創麵貼%傷口換藥%臨床療效%細菌檢齣率%抗菌%愈閤率%敷料
생물재료%재료상용성%갑각질의용창면첩%상구환약%림상료효%세균검출솔%항균%유합솔%부료
bandages%wound healing%chitosan
背景:甲壳质制备的创面材料具有减轻伤口疼痛、止血、促进伤口愈合作用,并且具有良好的生物相容性和抗菌性,通透性好,能通过体内酶自然降解。<br> 目的:对比分析采用甲壳质医用创面贴与常规敷料进行伤口换药处理的临床疗效。<br> 方法:纳入临床门诊换药治疗患者60例,按患者意愿分别采用甲壳质医用创面贴和常规敷料换药处理,每组30例。比较两组处理后3,7,14 d伤口愈合率、细菌检出率及目测类比评分,并记录两组的愈合时间和治疗费用。<br> 结果与结论:甲壳质医用创面贴组不同时间点伤口愈合率高于常规敷料换药组(P <0.05),不同时间点细菌检出阳性率、目测类比评分低于常规敷料换药组(P <0.05)。甲壳质医用创面贴组窗口愈合时间短于常规敷料换药组(P<0.05)。两组治疗费用比较差异无显著性意义。结果表明采用甲壳质医用创面贴处理创口可以有效促进伤口愈合,降低细菌感染率,患者治疗满意度较优。
揹景:甲殼質製備的創麵材料具有減輕傷口疼痛、止血、促進傷口愈閤作用,併且具有良好的生物相容性和抗菌性,通透性好,能通過體內酶自然降解。<br> 目的:對比分析採用甲殼質醫用創麵貼與常規敷料進行傷口換藥處理的臨床療效。<br> 方法:納入臨床門診換藥治療患者60例,按患者意願分彆採用甲殼質醫用創麵貼和常規敷料換藥處理,每組30例。比較兩組處理後3,7,14 d傷口愈閤率、細菌檢齣率及目測類比評分,併記錄兩組的愈閤時間和治療費用。<br> 結果與結論:甲殼質醫用創麵貼組不同時間點傷口愈閤率高于常規敷料換藥組(P <0.05),不同時間點細菌檢齣暘性率、目測類比評分低于常規敷料換藥組(P <0.05)。甲殼質醫用創麵貼組窗口愈閤時間短于常規敷料換藥組(P<0.05)。兩組治療費用比較差異無顯著性意義。結果錶明採用甲殼質醫用創麵貼處理創口可以有效促進傷口愈閤,降低細菌感染率,患者治療滿意度較優。
배경:갑각질제비적창면재료구유감경상구동통、지혈、촉진상구유합작용,병차구유량호적생물상용성화항균성,통투성호,능통과체내매자연강해。<br> 목적:대비분석채용갑각질의용창면첩여상규부료진행상구환약처리적림상료효。<br> 방법:납입림상문진환약치료환자60례,안환자의원분별채용갑각질의용창면첩화상규부료환약처리,매조30례。비교량조처리후3,7,14 d상구유합솔、세균검출솔급목측류비평분,병기록량조적유합시간화치료비용。<br> 결과여결론:갑각질의용창면첩조불동시간점상구유합솔고우상규부료환약조(P <0.05),불동시간점세균검출양성솔、목측류비평분저우상규부료환약조(P <0.05)。갑각질의용창면첩조창구유합시간단우상규부료환약조(P<0.05)。량조치료비용비교차이무현저성의의。결과표명채용갑각질의용창면첩처리창구가이유효촉진상구유합,강저세균감염솔,환자치료만의도교우。
BACKGROUND:The chitin medical wound dressing can relieve the wound pain, bleeding, and promote wound healing. It has good biocompatibility and antibacterial properties. With the good permeability and natural <br> degradation in the body, it can be used clinicaly as a good biological wound dressing. <br> OBJECTIVE: To evaluate the clinical outcome of the chitin medical wound dressing paste and routine dressings used in changing the dressing and medication. <br> METHODS:We retrospectively studied 60 patients undergoing wound-treatment. They were divided into two <br> groups: chitin medical wound dressing paste group and routine dressing group. Each group had 30 patients. We recorded wound healing rate, detection rate of bacteria, visual analog scale score, healing time and cost of <br> treatment at 3, 7, 14 days after treatment. <br> RESULTS AND CONCLUSION: The wound healing rate, detection rate of bacteria, visual analog scale score, healing time of the chitin medical wound dressing paste group were better than those of the routine dressing change medicine group (P < 0.05). But there was no difference in the cost of treatment between the two groups. Therefore, we can made the conclusion that the chitin medical wound dressing paste used in changing the <br> dressing and medication can promote wound healing, reduce the antibacterial infection rate, and obtain better treatment satisfaction.