CAJ | 학술논문

小鼠、大鼠糖尿病模型对基础与临床防治研究十分重要，不同的研究目标对应不同的动物模型载体。本文就目前常用的2型糖尿病鼠类模型的构建、主要疾病特征及应用等进行评述，为研究者了解、选择适合的动物模型提供参考。
소서、대서당뇨병모형대기출여림상방치연구십분중요，불동적연구목표대응불동적동물모형재체。본문취목전상용적2형당뇨병서류모형적구건、주요질병특정급응용등진행평술，위연구자료해、선택괄합적동물모형제공삼고。
Mouse and rat models of type 2 diabetes mellitus play a key role in basic and clinical translational stud-ies.Different animal models should match the determined investigational objects and methods .In this review, the estab-lishments and diabetes-specific changes of various animal models were described , which will be helpful for better use of ani-mal models in research of diabetes mellitus .