CAJ | 학술논문

目的：总结分析不同溶栓药物治疗冠心病的临床疗效和不良反应情况。方法选择2012年1月-2012年12月期间我院收治的80例冠心病患者为研究对象，随机分为研究1组和研究2组各40例，研究1组患者给予阿司匹林治疗，研究2组患者给予氯吡格雷药物治疗，观察并比较两组患者的治疗效果和不良反应情况。结果治疗后研究2组血小板聚集率、CRP 明显低于研究1组（P ﹤0.05）；研究2组治疗总有效率明显高于研究1组（P ﹤0.05）；研究2组不良反应发生率明显低于研究1组（P ﹤0.05）。结论与阿司匹林相比，氯吡格雷在冠心病患者溶栓治疗中疗效更佳，不良反应更少，临床值得推广使用。
목적：총결분석불동용전약물치료관심병적림상료효화불량반응정황。방법선택2012년1월-2012년12월기간아원수치적80례관심병환자위연구대상，수궤분위연구1조화연구2조각40례，연구1조환자급여아사필림치료，연구2조환자급여록필격뢰약물치료，관찰병비교량조환자적치료효과화불량반응정황。결과치료후연구2조혈소판취집솔、CRP 명현저우연구1조（P ﹤0.05）；연구2조치료총유효솔명현고우연구1조（P ﹤0.05）；연구2조불량반응발생솔명현저우연구1조（P ﹤0.05）。결론여아사필림상비，록필격뢰재관심병환자용전치료중료효경가，불량반응경소，림상치득추엄사용。
Objective:To investigate clinical efficacy and adverse reactions of different thrombolytic drugs in treatment of coronary heart disease. Methods:Eighty patients with coronary heart disease in our hospital from January 2012 to Decem-ber 2012 were selected and divided into study group 1(40)treated by aspirin and study group 2(40)treated by clopi-dogrel. The Therapeutic effects and adverse reactions of two groups were compared. Results:After treatment,the platelet aggregation rate and CRP of study group 2 were significantly lower than those of the study group 1( P ﹤ 0. 05 ). The total efficiency of study group 2 was significantly higher than that of the study group 1(P ﹤ 0. 05). The adverse reactions rate of study group 2 was significantly higher than that of the study group 1(P ﹤ 0. 05). Conclusion:Compared with aspirin,clo-pidogrel thrombolytic therapy in patients with coronary artery disease has better efficacy and fewer side effects.