中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2012年
24期
3716-3717
,共2页
甲状腺肿瘤%肿瘤复发,局部%抗肿瘤联合化疗方案
甲狀腺腫瘤%腫瘤複髮,跼部%抗腫瘤聯閤化療方案
갑상선종류%종류복발,국부%항종류연합화료방안
Thyroid neoplasms%Neoplasm recurrence,local%Antineoplastic combined chemotherapy protocols
目的 观察放疗、化疗粒子联合植入法治疗复发性甲状腺癌的疗效.方法 选取16例经过放疗治疗和手术后均再次复发的甲状腺癌患者,随机分成观察组与对照组各8例,观察组患者采用放疗、化疗粒子联合植入法进行治疗,在B超引导下将氟尿嘧啶缓释化疗粒子和125(I)粒子以交替的方式植入;对照组单纯进行放化疗治疗.观察比较两组临床治疗效果.结果 两组均顺利完成治疗计划,未发生任何并发症状及神经损伤或气管损伤.治疗后X线平片检查:观察组所植入的放射粒子的位置均未发生任何变化.治疗后6个月对肿瘤进行CT检查,两组肿瘤体积均在一定程度上有所减小.观察组:完全缓解2例,部分缓解5例,无明显变化1例;对照组:完全缓解1例,部分缓解5例,无明显变化2例;两组临床治疗效果差异有统计学意义(P＜0.05).随访1年,观察组无1例患者死亡,对照组死亡1例.结论 采用放疗、化疗粒子联合植入法治疗复发性甲状腺癌,临床效果好,值得临床推广应用.
目的 觀察放療、化療粒子聯閤植入法治療複髮性甲狀腺癌的療效.方法 選取16例經過放療治療和手術後均再次複髮的甲狀腺癌患者,隨機分成觀察組與對照組各8例,觀察組患者採用放療、化療粒子聯閤植入法進行治療,在B超引導下將氟尿嘧啶緩釋化療粒子和125(I)粒子以交替的方式植入;對照組單純進行放化療治療.觀察比較兩組臨床治療效果.結果 兩組均順利完成治療計劃,未髮生任何併髮癥狀及神經損傷或氣管損傷.治療後X線平片檢查:觀察組所植入的放射粒子的位置均未髮生任何變化.治療後6箇月對腫瘤進行CT檢查,兩組腫瘤體積均在一定程度上有所減小.觀察組:完全緩解2例,部分緩解5例,無明顯變化1例;對照組:完全緩解1例,部分緩解5例,無明顯變化2例;兩組臨床治療效果差異有統計學意義(P＜0.05).隨訪1年,觀察組無1例患者死亡,對照組死亡1例.結論 採用放療、化療粒子聯閤植入法治療複髮性甲狀腺癌,臨床效果好,值得臨床推廣應用.
목적 관찰방료、화료입자연합식입법치료복발성갑상선암적료효.방법 선취16례경과방료치료화수술후균재차복발적갑상선암환자,수궤분성관찰조여대조조각8례,관찰조환자채용방료、화료입자연합식입법진행치료,재B초인도하장불뇨밀정완석화료입자화125(I)입자이교체적방식식입;대조조단순진행방화료치료.관찰비교량조림상치료효과.결과 량조균순리완성치료계화,미발생임하병발증상급신경손상혹기관손상.치료후X선평편검사:관찰조소식입적방사입자적위치균미발생임하변화.치료후6개월대종류진행CT검사,량조종류체적균재일정정도상유소감소.관찰조:완전완해2례,부분완해5례,무명현변화1례;대조조:완전완해1례,부분완해5례,무명현변화2례;량조림상치료효과차이유통계학의의(P＜0.05).수방1년,관찰조무1례환자사망,대조조사망1례.결론 채용방료、화료입자연합식입법치료복발성갑상선암,림상효과호,치득림상추엄응용.
Objective To observe the effect of recurrent thyroid cancer patients treatment with radiotherapy,chemotherapy particle implantation after targeted therapy.Methods 16 thyroid cancer patients after radiotherapy and operation relapsed were seldcted.The patients were randomly divided into the treatment group and the control group,the patients in the treatment group treated with radiotherapy,chemotherapy combined with implantation of targeted for their treatment,through the treatment plan effective vaginal B ultrasound guided,in the 5-FU Sustained-release chemotherapy particle and a 125(I)particle in alternating fashion to the implant,the patients of control group treated with chemoradiation therapy.Results 16 patients were all successfully operated.On postoperative patients during the followup for half a year,the treatment group adopted CT reexamined patients tumor can be narrowed,which completely in 2 cases,partial remission in 5 patients,1 patient had no significant changes compared with the control group,the difference was statistically significant;follow-up of 1 year,prior treatment groups of all patients are in the survival condition,the control group had 1 patient died.Conclusion For recurrent thyroid cancer patients given radiotherapy and chemotherapy,combination with particle implantation targeted treatment,have good effect,which belongs to an effective means of treatment,can be widely used in clinical.
