CAJ | 학술논문

目的：了解大理州无偿献血者Rh（D）阴性血型的血清学表现型及不规则抗体存在情况。方法：检测献血者样本136803例，采用血清学方法确证Rh表现型，使用抗人球蛋白试剂对不规则抗体作筛查。结果：确证Rh（D）阴性献血者209例（0.15%）；其中含不规则抗体1例（0.48%），血清学表现型中：ccdee 123例（58.85%），Ccdee 67例（32.06%），CCdee 7例（3.35%）， ccdEe 6例（2.87%），CcdEe 5例（2.39%），CCdEe 1例（0.48%）。该阴性献血者ABO血型分布情况A＞O＞B＞AB。结论：对献血者Rh（D）阴性血型的血清学表现型及不规则抗体作检测，将有利于为临床安全及时有效输血提供保障。
목적：료해대리주무상헌혈자Rh（D）음성혈형적혈청학표현형급불규칙항체존재정황。방법：검측헌혈자양본136803례，채용혈청학방법학증Rh표현형，사용항인구단백시제대불규칙항체작사사。결과：학증Rh（D）음성헌혈자209례（0.15%）；기중함불규칙항체1례（0.48%），혈청학표현형중：ccdee 123례（58.85%），Ccdee 67례（32.06%），CCdee 7례（3.35%）， ccdEe 6례（2.87%），CcdEe 5례（2.39%），CCdEe 1례（0.48%）。해음성헌혈자ABO혈형분포정황A＞O＞B＞AB。결론：대헌혈자Rh（D）음성혈형적혈청학표현형급불규칙항체작검측，장유리우위림상안전급시유효수혈제공보장。
Objective:To investigate serological phenotype and to detect irregular antibody among Rh(D)negative blood donors in Dali Prefecture. Methods: 136 803 blood samples were detected to determine the Rh phenotypes through serological tests and the irregular antibodies were screened through antiglobulin tests. Results: 209 blood samples were Rh (D) negative (0.15%). The irregular antibodies were found in one Rh(D)negative sample(0.48%). The serological phenotypes included 123 ccdee(58.85%), 67 Ccdee(32.06%), 7 CCdee(3.35%), 6 ccdEe(2.87%), 5 CcdEe(2.39%)and 1 CcdEe(0.48%). Among all Rh(D)negative volunteer blood donors, the distribution of A, B, O and AB blood types was A>O>B>AB. Conclusion: The study of serological phenotype and irregular antibody of Rh(D)negative blood donors would be helpful for enhancing the clinical safety and timely blood transfusion.