中国实验诊断学
中國實驗診斷學
중국실험진단학
CHINESE JOURNAL OF LABORATORY DIAGNOSIS
2014年
8期
1250-1252
,共3页
高双苓%王建桥%王学仕%李战永
高雙苓%王建橋%王學仕%李戰永
고쌍령%왕건교%왕학사%리전영
短暂性脑缺血发作%脑梗死%血管狭窄/闭塞%风险评估
短暫性腦缺血髮作%腦梗死%血管狹窄/閉塞%風險評估
단잠성뇌결혈발작%뇌경사%혈관협착/폐새%풍험평고
transient ischemic attack%cerebral infarction%vascular stenosis or occlusion%risk assessment
目的：探讨颅内血管狭窄与短暂性脑缺血发作（transient ischemic attack，TIA）1周内转化为脑梗死的关系。方法临床收集121例 TIA 患者，观察患者住院1周内转化为脑梗死的百分率。查颅脑磁共振弥散加权成像（DWI）判断患者有无新鲜脑梗死，采用头颈 CT 血管造影（CTA）方法，检查所有患者颅内血管狭窄程度，分析颅内血管狭窄程度、部位、数量与 TIA 进展为脑梗死的关系。结果121例 TIA 患者中，35例在发病1周内发生脑梗死（28．9％进展为脑梗死）。79例患者存在颅内血管狭窄，其中轻度狭窄36例、中度狭窄29例、重度狭窄14例。TIA后脑梗死的发生率与颅内动脉狭窄程度呈正相关（P ＜0．01），与颅内动脉责任血管狭窄、近端血管狭窄显著相关（P ＜0．01），多发脑血管狭窄导致 TIA 早期脑梗死的发生率明显升高（P ＜0．01）。结论颅内血管狭窄是 TIA 早期转化为脑梗死的独立危险因素，颅内血管检查有助于 TIA 患者早期转化为脑梗死的风险评估。
目的：探討顱內血管狹窄與短暫性腦缺血髮作（transient ischemic attack，TIA）1週內轉化為腦梗死的關繫。方法臨床收集121例 TIA 患者，觀察患者住院1週內轉化為腦梗死的百分率。查顱腦磁共振瀰散加權成像（DWI）判斷患者有無新鮮腦梗死，採用頭頸 CT 血管造影（CTA）方法，檢查所有患者顱內血管狹窄程度，分析顱內血管狹窄程度、部位、數量與 TIA 進展為腦梗死的關繫。結果121例 TIA 患者中，35例在髮病1週內髮生腦梗死（28．9％進展為腦梗死）。79例患者存在顱內血管狹窄，其中輕度狹窄36例、中度狹窄29例、重度狹窄14例。TIA後腦梗死的髮生率與顱內動脈狹窄程度呈正相關（P ＜0．01），與顱內動脈責任血管狹窄、近耑血管狹窄顯著相關（P ＜0．01），多髮腦血管狹窄導緻 TIA 早期腦梗死的髮生率明顯升高（P ＜0．01）。結論顱內血管狹窄是 TIA 早期轉化為腦梗死的獨立危險因素，顱內血管檢查有助于 TIA 患者早期轉化為腦梗死的風險評估。
목적：탐토로내혈관협착여단잠성뇌결혈발작（transient ischemic attack，TIA）1주내전화위뇌경사적관계。방법림상수집121례 TIA 환자，관찰환자주원1주내전화위뇌경사적백분솔。사로뇌자공진미산가권성상（DWI）판단환자유무신선뇌경사，채용두경 CT 혈관조영（CTA）방법，검사소유환자로내혈관협착정도，분석로내혈관협착정도、부위、수량여 TIA 진전위뇌경사적관계。결과121례 TIA 환자중，35례재발병1주내발생뇌경사（28．9％진전위뇌경사）。79례환자존재로내혈관협착，기중경도협착36례、중도협착29례、중도협착14례。TIA후뇌경사적발생솔여로내동맥협착정도정정상관（P ＜0．01），여로내동맥책임혈관협착、근단혈관협착현저상관（P ＜0．01），다발뇌혈관협착도치 TIA 조기뇌경사적발생솔명현승고（P ＜0．01）。결론로내혈관협착시 TIA 조기전화위뇌경사적독립위험인소，로내혈관검사유조우 TIA 환자조기전화위뇌경사적풍험평고。
Objective To investigate the function of intracranial artery stenosis or occlusion to early stroke risk after transient ischemic attack (TIA)at 7 days.Methods 121 consecutive patients with a clinical diagnosis of TIA in whom diffusion weighted imaging (DWI)and CT angiography (CTA)were performed within 24 hours of symptom onset. DWI was reviewed to diognose cerebral infarction after TIA and the stroke rate was calculated.Stenosis or occlusion of symptomatic intracranial arteries for recurrent stroke at 7 days after TIA was analysed.The characteristics of steno-oc-clusive lesions included the position,degree and the number.Results Of 121 TIA patients,35 cases developed into cere-bral infarction,and 79 cases were found intracranial arteries stenosis or occlusion (36 for mild stenosis,29 for moderate stenosis and 14 for serve stenosis).The stroke rate was 28.9%.The cerebral infarction after TIA at 7 days was signifi-cantly ralated with the stenosis of criminal arteries and proximal large intracranial arteries(P <0.01),as well as the moderate and serve stenosis and multiple cerebral vascular stenosis of intracranial arteries(P <0.01).Conclusion Cer-ebral vascular stenosis was the independent risk factor of early stroke after TIA at 7 days.To eveluate the intracranial artery stenosis or occlusion help to predict the early risk of cerebral infarction after TIA.
