CAJ | 학술논문

目的：探讨泌尿系感染与肾结石的关系及抗感染治疗对预后的影响。方法回顾性分析38例自2011年11月至2013年3月间在本中心行手术治疗的肾结石患者的临床资料，患者均为原发性单侧肾结石或单侧肾结石合并输尿管结石，手术方式为PCNL或者PCNL、URL相结合，术前所有尿常规WBC升高病人均行经验性抗感染治疗，尿培养结果阳性者则根据药敏结果行抗感染治疗，疗程为3～16天；术后所有病人均应用抗生素抗感染治疗3～15天，术后随访时间为12～29个月。文章主要分析患者是否合并感染症状、尿常规及尿培养结果、术前抗感染治疗时间、术后抗感染治疗情况，并跟踪随访其院外是否存在泌尿系感染及结石复发。结果术后跟踪随访时间为12～29个月，复发者5例，其中尿常规阴性出院者共30人，复发1例；尿常规WBC升高者8例，出院后均未用抗生素规范治疗，4例复发。结论患者复发率与泌尿系炎症控制情况具有相关性；合理应用抗生素控制尿路感染对于预防泌尿系结石复发具有一定效果。
목적：탐토비뇨계감염여신결석적관계급항감염치료대예후적영향。방법회고성분석38례자2011년11월지2013년3월간재본중심행수술치료적신결석환자적림상자료，환자균위원발성단측신결석혹단측신결석합병수뇨관결석，수술방식위PCNL혹자PCNL、URL상결합，술전소유뇨상규WBC승고병인균행경험성항감염치료，뇨배양결과양성자칙근거약민결과행항감염치료，료정위3～16천；술후소유병인균응용항생소항감염치료3～15천，술후수방시간위12～29개월。문장주요분석환자시부합병감염증상、뇨상규급뇨배양결과、술전항감염치료시간、술후항감염치료정황，병근종수방기원외시부존재비뇨계감염급결석복발。결과술후근종수방시간위12～29개월，복발자5례，기중뇨상규음성출원자공30인，복발1례；뇨상규WBC승고자8례，출원후균미용항생소규범치료，4례복발。결론환자복발솔여비뇨계염증공제정황구유상관성；합리응용항생소공제뇨로감염대우예방비뇨계결석복발구유일정효과。
Objective There has been proved to be a close relationship between urinary stone disease and u-rinary tract infection,and we try to clarify this relationship and get a better understanding of how anti-infection therapy can affect the prognosis of kidney stone. Methods Review of 38 patients from November 2011 to March 2013 from Minimally Invasive Urology Center of Shandong Provincial Hospital. The patients we choose all have unilateral kidney stones or accompanied with ureter stone disease and had successful surgeries. All patients had anti-infection therapy time 3~16 days in the pre-operation and had anti-infection therapy 3~15 days in the post-operation until clinical symptoms were removed. They had been followed-up for 12~29 months. Results After 12~29 months'follow-up study,5 patients had a relapse. Of the 30 patients with negative urinalysis or rational anti-infection therapy,1 patients had a recurrence kidney stone. Of the 8 patients with positive results or without rational anti-infection therapy there are 4 patients had a relapse. Conclusions Anti-infection thera-py could be used in preventing the recurrence of non-infection stone disease as well as infection stones.