药物不良反应杂志
藥物不良反應雜誌
약물불량반응잡지
ADVERSE DRUG REACTIONS JOURNAL
2014年
4期
252-253
,共2页
瑞舒伐他汀%高血糖症
瑞舒伐他汀%高血糖癥
서서벌타정%고혈당증
rosuvastatin%Hyperglycemia
1例74岁男性冠状动脉粥样硬化性心脏病患者于冠状动脉支架植入术后应用硫酸氢氯吡格雷、阿司匹林、通心络、辅酶Q10、阿托伐他汀钙、维生素E及维生素C。因降脂效果不达标,患者自行停用阿托伐他汀钙,改服瑞舒伐他汀钙10 mg,1次/d。随后4个月,患者血糖水平较前升高,空腹血糖波动于6.5~7.8 mmol/L,餐后血糖波动于7.7~10.5 mmol/L。7个月后,患者空腹血糖达11.5 mmol/L,餐后血糖达16.0 mmol/L,糖化血红蛋白9.6%。患者自行停用瑞舒伐他汀钙。3个月后,空腹血糖降至5.9 mmol/L,餐后血糖降至7.4 mmol/L,糖化血红蛋白降至6.6%。
1例74歲男性冠狀動脈粥樣硬化性心髒病患者于冠狀動脈支架植入術後應用硫痠氫氯吡格雷、阿司匹林、通心絡、輔酶Q10、阿託伐他汀鈣、維生素E及維生素C。因降脂效果不達標,患者自行停用阿託伐他汀鈣,改服瑞舒伐他汀鈣10 mg,1次/d。隨後4箇月,患者血糖水平較前升高,空腹血糖波動于6.5~7.8 mmol/L,餐後血糖波動于7.7~10.5 mmol/L。7箇月後,患者空腹血糖達11.5 mmol/L,餐後血糖達16.0 mmol/L,糖化血紅蛋白9.6%。患者自行停用瑞舒伐他汀鈣。3箇月後,空腹血糖降至5.9 mmol/L,餐後血糖降至7.4 mmol/L,糖化血紅蛋白降至6.6%。
1례74세남성관상동맥죽양경화성심장병환자우관상동맥지가식입술후응용류산경록필격뢰、아사필림、통심락、보매Q10、아탁벌타정개、유생소E급유생소C。인강지효과불체표,환자자행정용아탁벌타정개,개복서서벌타정개10 mg,1차/d。수후4개월,환자혈당수평교전승고,공복혈당파동우6.5~7.8 mmol/L,찬후혈당파동우7.7~10.5 mmol/L。7개월후,환자공복혈당체11.5 mmol/L,찬후혈당체16.0 mmol/L,당화혈홍단백9.6%。환자자행정용서서벌타정개。3개월후,공복혈당강지5.9 mmol/L,찬후혈당강지7.4 mmol/L,당화혈홍단백강지6.6%。
A 74-year-old male patient with coronary atherosclerotic heart disease given clopidogrel hydrogen sulfate,aspirin,Tongxinluo(通心络),coenzyme Q10 ,atorvastatin calcium,vitamin E and vitamin C after undergoing coronary artery stent implantation. He stopped taking atorvastatin calcium because of the lipid-lowering effect was not good and switched to rosuvastatin calcium 10 mg once daily by himself. The patient's blood glucose level elevated within four months. His fasting blood glucose ranged from 6. 5 to 7. 8 mmol/L and postprandial blood glucose ranged from 7. 7 to 10. 5 mmol/L. Seven months later,his fasting blood glucose peaked at 11. 5 mmol/L,and postprandial blood glucose peaked at 16. 0 mmol/L, glycosylated hemoglobin level was 9. 6%. He discontinued rosuvastatin calcium by himself. Three months later,the fasting blood glucose and postprandial blood glucose were down to 5. 9 mmol/L and 7. 4 mmol/L, glycosylated hemoglobin level was back to 6. 6%.