药物不良反应杂志
藥物不良反應雜誌
약물불량반응잡지
ADVERSE DRUG REACTIONS JOURNAL
2014年
4期
250-251
,共2页
6-氨基己酸%血管性水肿,遗传性%头痛
6-氨基己痠%血管性水腫,遺傳性%頭痛
6-안기기산%혈관성수종,유전성%두통
6-Aminocaproic acid%Angioedema,hereditary%Headache
1例17岁女性患者确诊为Ⅰ型遗传性血管性水肿后给予6-氨基己酸4 g/d静脉滴注。第1次用药约1h时患者出现头痛、恶心，逐渐发展为双颞侧剧烈跳痛，伴全身乏力、精神萎靡、行动困难等症状，静脉滴注结束后约1h上述症状消失。第1~8天静脉滴注6-氨基己酸后上述症状复现，且逐日加重，均在用药结束后约1h症状消失。
1例17歲女性患者確診為Ⅰ型遺傳性血管性水腫後給予6-氨基己痠4 g/d靜脈滴註。第1次用藥約1h時患者齣現頭痛、噁心，逐漸髮展為雙顳側劇烈跳痛，伴全身乏力、精神萎靡、行動睏難等癥狀，靜脈滴註結束後約1h上述癥狀消失。第1~8天靜脈滴註6-氨基己痠後上述癥狀複現，且逐日加重，均在用藥結束後約1h癥狀消失。
1례17세녀성환자학진위Ⅰ형유전성혈관성수종후급여6-안기기산4 g/d정맥적주。제1차용약약1h시환자출현두통、악심，축점발전위쌍섭측극렬도통，반전신핍력、정신위미、행동곤난등증상，정맥적주결속후약1h상술증상소실。제1~8천정맥적주6-안기기산후상술증상복현，차축일가중，균재용약결속후약1h증상소실。
A 17-year-old female who was diagnosed as typeⅠhereditary angioedema( HAE-Ⅰ) received an IV infusion of 6-aminocaproic acid 4 g once daily. Headache and nausea appeared about one hour after the IV infusion and developed severe bitemporal headache accompanied with weakness,mental fatigue and difficult to move. The symptoms were disappeared about one hour after the IV infusion finished. The above-mentioned symptoms were recurrent and ingravescent during the IV infusion of 6-aminocaproic acid from the second to the eighth days. The symptoms were disappeared about one hour after the IV infusion finished.
