CAJ | 학술논문

1例78岁女性患者因心肌梗死给予阿司匹林100 mg，1次/d口服；硫酸氢氯吡格雷75 mg，1次/d口服。次日晨，患者腹部及双下肢出现瘙痒、红斑。停用硫酸氢氯吡格雷，予氯雷他定10 mg，1次/d口服。1 h后瘙痒缓解、红斑消退。第1天，患者自行服用硫酸氢氯吡格雷75 mg，过敏症状再现，继续服用氯雷他定。4d后，患者行冠状动脉造影﹢经皮冠状动脉介入治疗。术后采用替格瑞洛（90 mg、1次/d口服）联合阿司匹林（100 mg，1次/d口服）抗血小板治疗，随访6个月无不适症状。
1례78세녀성환자인심기경사급여아사필림100 mg，1차/d구복；류산경록필격뢰75 mg，1차/d구복。차일신，환자복부급쌍하지출현소양、홍반。정용류산경록필격뢰，여록뢰타정10 mg，1차/d구복。1 h후소양완해、홍반소퇴。제1천，환자자행복용류산경록필격뢰75 mg，과민증상재현，계속복용록뢰타정。4d후，환자행관상동맥조영﹢경피관상동맥개입치료。술후채용체격서락（90 mg、1차/d구복）연합아사필림（100 mg，1차/d구복）항혈소판치료，수방6개월무불괄증상。
A 78-year-old female patient with myocardial infarction received oral aspirin 100 mg once daily and clopidogrel hydrogen sulfate 75 mg once daily. She developed pruritus and erythema on her abdomen and both lower extremities in the next morning. The clopidogrel hydrogen sulfate was discontinued and she was treated with loratadine 10 mg once daily. Her pruritus had improved and erythema had subsided after 1 hours. On day 1,the patient self-administered clopidogrel hydrogen sulfate 75 mg. She presented with anaphylactoid symptoms again and loratadine was continued. Four days later,the patient underwent coronary angiography and percutaneous coronary intervention. She received dual antiplatelet therapy with oral ticagrelor 90 mg twice daily and aspirin 100 mg once daily after surgery. The patient had no discomfort at 6 months follow-up.