CAJ | 학술논문

目的：探讨手术干预联合药物治疗真菌性角膜溃疡的临床疗效。方法对40例（40只眼）真菌性角膜溃疡患者在药物治疗同时，适时采用溃疡板层清创、溃疡板层清创联合前房冲洗或结膜瓣遮盖等手术治疗。随访≥3个月，观察治疗效果及预后。结果40例真菌溃疡患者，仅1例因角膜供体缺乏采取了球内容物剜除术，治疗总有效率97.5％（39/40），除去2例行穿透性角膜移植术治愈患者，有效率仍达92.5％（37/40）。结论在真菌性角膜溃疡药物治疗的同时，适时的采取手术干预及方式是一种行之有效的方法，适用于广大基层医院开展。
목적：탐토수술간예연합약물치료진균성각막궤양적림상료효。방법대40례（40지안）진균성각막궤양환자재약물치료동시，괄시채용궤양판층청창、궤양판층청창연합전방충세혹결막판차개등수술치료。수방≥3개월，관찰치료효과급예후。결과40례진균궤양환자，부1례인각막공체결핍채취료구내용물완제술，치료총유효솔97.5％（39/40），제거2례행천투성각막이식술치유환자，유효솔잉체92.5％（37/40）。결론재진균성각막궤양약물치료적동시，괄시적채취수술간예급방식시일충행지유효적방법，괄용우엄대기층의원개전。
Objective To study the outcomes of surgical interventions in the treatment of fungal corneal ulcer , and to look for an optimal strategy that could be widely used among primary ophthalmic care settings .Methods Totally 40 pa-tients (40 eyes) with fungal corneal ulcer were enrolled in this study .Besides topical antifungal agents , lamellar keratecto-my, or lamellar keratectomy combined with 0.02% fluconazole anterior chamber wash , or lamellar keratectomy combined with conjunctival flap covering were performed according to disease stages .The outcomes were evaluated during 3-month follow-up period.Results Most of our patients were successfully treated with above surgical interventions .One patient e-ventually underwent ocular enucleation .Two patients received penetrating keratoplasty and were cured .Overall success rate of lamellar keratectomy was 92.5% (37/40).Conclusion Appropriate surgical intervention is necessary to treat fungal corneal ulceration .Relatively simple procedures like lamellar keratectomy could be used even in primary hospitals .