CAJ | 학술논문

目的：探讨翼状胬肉切除联合角膜缘干细胞移植及附加综合辅助治疗措施治疗翼状胬肉的临床远期疗效。方法回顾分析113例（117只眼）翼状胬肉切除联合角膜缘干细胞移植术病例，其中65只眼仅行常规手术，52只眼行常规手术联合综合辅助治疗。结果65只眼仅行常规手术有4只眼复发，复发率为6.15％；52只眼行常规手术联合综合辅助治疗措施后2只眼复发，复发率为3.85％。经统计学分析， P ＜0.05，差异有统计学意义。结论翼状胬肉切除联合角膜缘干细胞移植术治疗翼状胬肉安全、有效，尽量排除不利因素，采取综合辅助治疗措施可更有效地减少民办状胬肉术后复发率。
목적：탐토익상노육절제연합각막연간세포이식급부가종합보조치료조시치료익상노육적림상원기료효。방법회고분석113례（117지안）익상노육절제연합각막연간세포이식술병례，기중65지안부행상규수술，52지안행상규수술연합종합보조치료。결과65지안부행상규수술유4지안복발，복발솔위6.15％；52지안행상규수술연합종합보조치료조시후2지안복발，복발솔위3.85％。경통계학분석， P ＜0.05，차이유통계학의의。결론익상노육절제연합각막연간세포이식술치료익상노육안전、유효，진량배제불리인소，채취종합보조치료조시가경유효지감소민판상노육술후복발솔。
Objective To evaluate and analyze the long-term efficacy and safety of combined pterygium excision and conjunctival autografting for the treatment of primary pterygium .Methods Subjects included 113 patients (117 eyes) with primary pterygium who were treated in our hospital with combined pterygium excision and conjunctival limbal autograft transplantation .Among the subjects , sixty-five eyes received surgery alone , and the other 52 eyes received surgery and tropical medication therapies .Conjunctival autografts were obtained from upper temporal limbus and secured with 10-0 mon-ofilament nylon.All patients were followed for 33 to 54 months (mean 39 months).Results In 65 eyes that underwent surgery alone, pterygium recurred in four (6.15%) eyes.In 52 eyes that received surgery and tropical mitomycin C and steroids, only two eyes (3.85%) were found to had recurred pterygium .This difference was significant ( P <0.05). Conclusion We conclude that combined pterygium excision and conjunctival limbal autografting is effective and safe for the treatment of primary pterygium .Addition of tropical medications such as mitomycin C and steroids would further reduce the risk of recurrence .