CAJ | 학술논문

目的探讨前列地尔治疗糖尿病患者勃起功能障碍的疗效.方法将90例糖尿病合并勃起功能障碍患者按就诊顺序随机分为观察组(45例,伐地那非+前列地尔)和对照组(45例,伐地那非),疗程3月,比较两组阴茎的硬度、勃起时间、IIEF-5评分情况.结果观察组与对照组比较,阴茎的硬度满意度(29％ vs 18％)、勃起时间[(5.6±1.2)分vs(1.2±0.6)分]、IIEF-5评分[(22.1±2.3)分vs(17.5±1.9)分],观察组均有明显升高(P＜ 0.05,差异具有统计学意义)；观察组有3例发生不良反应,其中面色潮红2例、静脉炎1例.结论在伐地那非基础上加用前列地尔治疗可进一步改善糖尿病合并勃起功能障碍患者的勃起功能,且不良反应少.
목적 탐토전렬지이치료당뇨병환자발기공능장애적료효.방법 장90례당뇨병합병발기공능장애환자안취진순서수궤분위관찰조(45례,벌지나비+전렬지이)화대조조(45례,벌지나비),료정3월,비교량조음경적경도、발기시간、IIEF-5평분정황.결과 관찰조여대조조비교,음경적경도만의도(29％ vs 18％)、발기시간[(5.6±1.2)분vs(1.2±0.6)분]、IIEF-5평분[(22.1±2.3)분vs(17.5±1.9)분],관찰조균유명현승고(P＜ 0.05,차이구유통계학의의)；관찰조유3례발생불량반응,기중면색조홍2례、정맥염1례.결론 재벌지나비기출상가용전렬지이치료가진일보개선당뇨병합병발기공능장애환자적발기공능,차불량반응소.
Objective To investigate the efficacy of alprostadil for erectile dysfunction (ED) in patients with diabetes mellitus.Methods Ninety diabetic patients with erectile dysfunction were randomized to receive either vardenafil plus alprostadi (study group,n =45),or vardenafil alone (control group,n=45) for 3 months.The rate of satisfaction with erection hardness,duration of erection,and IIEF-5 score were compared between the two groups.Results The rate of satisfaction rate with erection hardness,duration of erection,and IIEF-5 score were better in the study group than in the control group (29％ vs.18％,5.6 + 1.2 min vs.1.2 + 0.6 min,and 22.1 ± 2.3 vs.17.5 + 1.9;P＜0.05).Adverse reactions occurred in three patients including facial flushing in two and phlebitis in one.Conclusions Alprostadil combined with vardenafil can further improve erection dysfunction in patients with diabetes mellitus and has few adverse reactions.