医学分子生物学杂志
醫學分子生物學雜誌
의학분자생물학잡지
FOREIGN MEDICAL SCIENCES
2014年
4期
240-243
,共4页
杨新%李梦婷%曾之晅%沈关心
楊新%李夢婷%曾之晅%瀋關心
양신%리몽정%증지훤%침관심
Treg细胞%慢性代谢性疾病%免疫治疗
Treg細胞%慢性代謝性疾病%免疫治療
Treg세포%만성대사성질병%면역치료
Treg cells%chronic metabolic diseases%immune therapeutics
免疫微环境的稳态与代谢过程关系密切,调节性T细胞(regulatory T cells, Treg)是一类具有免疫调节功能的T细胞亚群,参与外周免疫耐受,有关Treg细胞的研究一直是免疫学领域的热点。近年来慢性代谢性疾病的发病率逐年上升,但是治疗方法有限,有学者发现了Treg细胞在这些疾病的发生发展中极为重要,对慢性代谢性疾病的治疗具有重要意义。
免疫微環境的穩態與代謝過程關繫密切,調節性T細胞(regulatory T cells, Treg)是一類具有免疫調節功能的T細胞亞群,參與外週免疫耐受,有關Treg細胞的研究一直是免疫學領域的熱點。近年來慢性代謝性疾病的髮病率逐年上升,但是治療方法有限,有學者髮現瞭Treg細胞在這些疾病的髮生髮展中極為重要,對慢性代謝性疾病的治療具有重要意義。
면역미배경적은태여대사과정관계밀절,조절성T세포(regulatory T cells, Treg)시일류구유면역조절공능적T세포아군,삼여외주면역내수,유관Treg세포적연구일직시면역학영역적열점。근년래만성대사성질병적발병솔축년상승,단시치료방법유한,유학자발현료Treg세포재저사질병적발생발전중겁위중요,대만성대사성질병적치료구유중요의의。
Homeostasis of immune microenvironment is closely related to metabolic proces-ses.Regulatory T cells (Treg cells) are a subset of T lymphocytes that can regulate immune function and participate in peripheral immune tolerance.Treg cells have been hotspots in the study of immu-nology.Recently, the incidence of chronic metabolic diseases is rising by year , but the treatment outcomes are unsatisfactory.It was found that Treg cells play an important role in the occurrence and development of chronic metabolic diseases and they are of great significance in the treatment of these diseases.