CAJ | 학술논문

自噬是指双层膜包裹细胞内细胞器、蛋白质等物质形成自噬体，并与内体形成自噬内体，最终与溶酶体融合形成自噬溶酶体，降解其所包裹内容物，以实现细胞稳态的过程。多种激酶、磷酸酶、鸟苷三磷酸酶（ GTP酶）参与了自噬的形成过程。近年研究发现Rab GTPases家族中的许多分子在自噬形成过程中发挥中重要作用。
자서시지쌍층막포과세포내세포기、단백질등물질형성자서체，병여내체형성자서내체，최종여용매체융합형성자서용매체，강해기소포과내용물，이실현세포은태적과정。다충격매、린산매、조감삼린산매（ GTP매）삼여료자서적형성과정。근년연구발현Rab GTPases가족중적허다분자재자서형성과정중발휘중중요작용。
Autophagy is an evolutionarily conserved process in which cytoplasmic contents ( in-cluding organelles and proteins ) are engulfed by a double-membrane autophagosome , which eventu-ally has its content degraded at lysosome.The main role of autophagy is to maintain intracellular ho-meostasis.Various kinases , phosphatases , and guanosine triphosphatases ( GTPases ) take part in the autophagy.Recently , it was found that many molecules of Rab GTPase family play a pivotal role in the process of autophagy.