CAJ | 학술논문

目的：探讨丙泊酚复合利多卡因静脉麻醉在高血压患者结肠镜检查中的安全性及效果。方法回顾性分析47例高血压患者的结肠镜检查资料，将其分为常规组、无痛组。无痛组静脉缓慢注射丙泊酚和利多卡因混合液，使患者入睡后进镜检查。监测并记录两组在检查前、检查中、检查后的收缩压、舒张压、心率、血氧饱和度及镜检时间。无痛组记录麻醉诱导时间、苏醒时间、计算力及提问对答恢复正常时间。结果无痛组全部到达检查终点，常规组有2例未达到回盲部；无痛组镜检时间明显低于常规组，两组比较差异有统计学意义（P＜0.05）；无痛组的收缩压、舒张压、心率在检查中较检查前明显下降（P＜0.05）；常规组收缩压、舒张压、心率在检查中比检查前明显增高（P＜0.05）；两组检查结束后收缩压、舒张压、心率均恢复至检查前水平；血氧饱和度在两组的各个检查中无明显变化。无痛组麻醉诱导时间为（1.9±0.6）min、清醒时间为（6±5）min，计算力及提问对答恢复正常时间为（6±5）min。结论应用丙泊酚复合利多卡因静脉麻醉对高血压患者进行无痛结肠镜检查是可靠的。
목적：탐토병박분복합리다잡인정맥마취재고혈압환자결장경검사중적안전성급효과。방법회고성분석47례고혈압환자적결장경검사자료，장기분위상규조、무통조。무통조정맥완만주사병박분화리다잡인혼합액，사환자입수후진경검사。감측병기록량조재검사전、검사중、검사후적수축압、서장압、심솔、혈양포화도급경검시간。무통조기록마취유도시간、소성시간、계산력급제문대답회복정상시간。결과무통조전부도체검사종점，상규조유2례미체도회맹부；무통조경검시간명현저우상규조，량조비교차이유통계학의의（P＜0.05）；무통조적수축압、서장압、심솔재검사중교검사전명현하강（P＜0.05）；상규조수축압、서장압、심솔재검사중비검사전명현증고（P＜0.05）；량조검사결속후수축압、서장압、심솔균회복지검사전수평；혈양포화도재량조적각개검사중무명현변화。무통조마취유도시간위（1.9±0.6）min、청성시간위（6±5）min，계산력급제문대답회복정상시간위（6±5）min。결론응용병박분복합리다잡인정맥마취대고혈압환자진행무통결장경검사시가고적。
Objective To investigate the safety and efficacy of anesthesia via propofol and lidocaine combined intravenous injection in hypertensive patients during the process of colonoscopy.Methods The colonoscopy data of 47 cases of hypertensive patients was retrospectively analyzed.The patients were divided into routine and painless groups.For the painless group,patients were intravenously administered propofol and lidocaine.After sleeping,the endoscopy study was performed.The systolic pressure,diastolic pressure,heart rate,oxygen saturation and examination time of the two groups were monitored and recorded,before,during and after the examination, respectively.The anesthesia induction time,recovery time,and calculating/answering recovering time of the painless group were recorded,respectively.Results Al patients in the painless group completed the examination, whereas the colonoscopy of 2 patients in the routine group did not reach the ileocecal;There was significant difference between two groups(P<0.05);for the painless group,the systolic and diastolic blood pressure,and heart rate during the inspection was significantly lower than that before the inspection(P<0.05);for the routine group,the systolic and diastolic blood pressure,and heart rate during the inspection was significantly increased compared with that before the inspection(P<0.05);after examination,the systolic and diastolic blood pressure and heart rate in both groups came back to the level before examination;the blood oxygen saturation did not shown significant difference during the examination for the two groups.For the painless group,the anesthesia induction time was(1.9 ±0.6)minutes;the awaking time was(6±5)minutes;the calculating/answering recovering time was (6± 5)minutes.Conclusion Anesthesia via propofol and lidocaine combined intravenous injection is reliable for the painless colonoscopy examination of patients with hypertension.