武汉体育学院学报
武漢體育學院學報
무한체육학원학보
JOURNAL OF WUHAN INSTITUTE OF PHYSICAL EDUCATION
2014年
8期
86-90
,共5页
AD患者%叶酸%Vit B12%尿甲醛%AD7c-NTP%乒乓球运动
AD患者%葉痠%Vit B12%尿甲醛%AD7c-NTP%乒乓毬運動
AD환자%협산%Vit B12%뇨갑철%AD7c-NTP%핑퐁구운동
AD patent%folic acid%Vatamin B12%urinary formaldehyde%AD7c-NTP%table tennis
目的：观察乒乓球运动结合补充叶酸、Vit B12对 AD(阿尔茨海默病)患者功能改善的影响。方法：选取2011年10月-2012年10月太原市符合CCMD-HE和NINCDS标准,并能积极配合观察的AD患者120例,随机分为实验组(60例)和对照组(60例)；对照组每日服用叶酸10mg,Vit B12500μg；实验组患者在对照组治疗基础上每隔一日进行1小时的乒乓球运动。运动干预时间为1年；在实验前后对对照组和实验组患者进MMSE (简易智力状态量表)和 ADL(日常生活活动能力量表)测定；采用荧光高效液相色谱法(HPLC)进行尿液甲醛检测,采用酶联免疫吸附测定(ELISA)法检测患者尿中AD7 c-NTP(神经丝蛋白)的含量。结果：与对照组65%的总有效率相比,实验组总有效率达到85%,乒乓球运动干预后实验组整体疗效明显优于对照组；对照组MMSE实验前后评分均值分别为(21.24±4.12)、(24.67±4.06),ADL为(24.86±4.35)、(20.56±4.65)；实验组MMSE 干预前后均值分别为(21.46±4.08)、(26.77±3.84),ADL为(25.34±4.56)、(20.06±5.24)；MMSE 评分实验组与对照组有显著性差异,ADL分值无明显差异；对照组尿中甲醛含量实验前后分别为(1.35±0.14)mmol/L、(0.45±0.07)mmol/L,尿中AD7c-NTP含量为(5.54±0.46)ng/mL、(2.75±0.62)ng/mL；实验组尿中甲醛含量前后分别为(1.32±0.34)mmol/L、(0.17±0.09)mmol/L,尿中AD7c-NTP含量为(5.02±0.56)ng/mL、(1.46±0.28)ng/mL；尿中甲醛和 AD7c-NTP 含量差异均有统计学意义。结论：乒乓球运动结合补充叶酸、Vit B12对AD患者功能改善具有明显作用；乒乓球运动可以作为AD患者的协助治疗。
目的：觀察乒乓毬運動結閤補充葉痠、Vit B12對 AD(阿爾茨海默病)患者功能改善的影響。方法：選取2011年10月-2012年10月太原市符閤CCMD-HE和NINCDS標準,併能積極配閤觀察的AD患者120例,隨機分為實驗組(60例)和對照組(60例)；對照組每日服用葉痠10mg,Vit B12500μg；實驗組患者在對照組治療基礎上每隔一日進行1小時的乒乓毬運動。運動榦預時間為1年；在實驗前後對對照組和實驗組患者進MMSE (簡易智力狀態量錶)和 ADL(日常生活活動能力量錶)測定；採用熒光高效液相色譜法(HPLC)進行尿液甲醛檢測,採用酶聯免疫吸附測定(ELISA)法檢測患者尿中AD7 c-NTP(神經絲蛋白)的含量。結果：與對照組65%的總有效率相比,實驗組總有效率達到85%,乒乓毬運動榦預後實驗組整體療效明顯優于對照組；對照組MMSE實驗前後評分均值分彆為(21.24±4.12)、(24.67±4.06),ADL為(24.86±4.35)、(20.56±4.65)；實驗組MMSE 榦預前後均值分彆為(21.46±4.08)、(26.77±3.84),ADL為(25.34±4.56)、(20.06±5.24)；MMSE 評分實驗組與對照組有顯著性差異,ADL分值無明顯差異；對照組尿中甲醛含量實驗前後分彆為(1.35±0.14)mmol/L、(0.45±0.07)mmol/L,尿中AD7c-NTP含量為(5.54±0.46)ng/mL、(2.75±0.62)ng/mL；實驗組尿中甲醛含量前後分彆為(1.32±0.34)mmol/L、(0.17±0.09)mmol/L,尿中AD7c-NTP含量為(5.02±0.56)ng/mL、(1.46±0.28)ng/mL；尿中甲醛和 AD7c-NTP 含量差異均有統計學意義。結論：乒乓毬運動結閤補充葉痠、Vit B12對AD患者功能改善具有明顯作用；乒乓毬運動可以作為AD患者的協助治療。
목적：관찰핑퐁구운동결합보충협산、Vit B12대 AD(아이자해묵병)환자공능개선적영향。방법：선취2011년10월-2012년10월태원시부합CCMD-HE화NINCDS표준,병능적겁배합관찰적AD환자120례,수궤분위실험조(60례)화대조조(60례)；대조조매일복용협산10mg,Vit B12500μg；실험조환자재대조조치료기출상매격일일진행1소시적핑퐁구운동。운동간예시간위1년；재실험전후대대조조화실험조환자진MMSE (간역지력상태량표)화 ADL(일상생활활동능역량표)측정；채용형광고효액상색보법(HPLC)진행뇨액갑철검측,채용매련면역흡부측정(ELISA)법검측환자뇨중AD7 c-NTP(신경사단백)적함량。결과：여대조조65%적총유효솔상비,실험조총유효솔체도85%,핑퐁구운동간예후실험조정체료효명현우우대조조；대조조MMSE실험전후평분균치분별위(21.24±4.12)、(24.67±4.06),ADL위(24.86±4.35)、(20.56±4.65)；실험조MMSE 간예전후균치분별위(21.46±4.08)、(26.77±3.84),ADL위(25.34±4.56)、(20.06±5.24)；MMSE 평분실험조여대조조유현저성차이,ADL분치무명현차이；대조조뇨중갑철함량실험전후분별위(1.35±0.14)mmol/L、(0.45±0.07)mmol/L,뇨중AD7c-NTP함량위(5.54±0.46)ng/mL、(2.75±0.62)ng/mL；실험조뇨중갑철함량전후분별위(1.32±0.34)mmol/L、(0.17±0.09)mmol/L,뇨중AD7c-NTP함량위(5.02±0.56)ng/mL、(1.46±0.28)ng/mL；뇨중갑철화 AD7c-NTP 함량차이균유통계학의의。결론：핑퐁구운동결합보충협산、Vit B12대AD환자공능개선구유명현작용；핑퐁구운동가이작위AD환자적협조치료。
The purpose of this study was to observe the effects of table tennis playing combined with folic acid,B12 on pa-tients with alzheimer's disease (AD).120 patients accordant with CCMD-HE and NINCDS standard were selected and randomly divided into experimental group and control group.Patients in the control group took a daily dose of 10mg folic acid and Vit B12 500 ug.Patients in the experimental group took the dose and took an hour table tennis exercise every one day for one year.Then the Mini Mental State Scale (MMSE)and activities of daily living scale (ADL)were measured. Meanwhile,the level of formaldehyde and neurofilament protein (AD7c-TP)in the urine was also detected by HPLC and control group,that of the experimental group was 85%. The curative effect for the experimental group was better than that of the control group (P < 0.05 ).The MMSE score mean before and after the experiment for the control group was (21.24 ±4.12)and (24.67 ±4.06).ADL was (25.34 ±4.56)and (20.06 ±5.24).There was signifi cant difference of MMSE (P <0.05)but not of ADL.For the control group,the level of formaldehyde before and after the experiment was (1.35 ±0.14)mmol/L,(0.45 ±0.07)mmol/L,AD7c-NTP (5.02 ±0.56)ng/mL,and (2.75± 0.62)ng/mL.There was significant difference of formaldehyde and AD7c-NTP content in urine (P <0.05).It could be concluded that the function of AD patients were significantly improved by the treatment with folic acid,Vit B12 combined with table tennis playing.
