CAJ | 학술논문

本试验旨在了解Ⅰ型、Ⅱ型酮病发生时奶牛体内某些理化参数的变化。在某集约化牛场随机选取产后7～28 d、平均胎次为2～3胎的试验奶牛，根据血浆中β-羟丁酸（BHBA）、葡萄糖（Glc）、游离脂肪酸（NEFA）的含量以及临床发病特点分为Ⅰ型酮病组（20头）、Ⅱ型酮病组（20头）和健康对照组（10头）。结果显示，三组间血浆中Glc、BH-BA、NEFA的浓度与体况评分存在显著差异（P＜0.05），但三组试验奶牛的泌乳量、产后天数、血浆中胰岛素（INS）含量彼此间无显著性差异（P＞0.05）。Ⅰ型酮病、Ⅱ型酮病与健康对照组之间的理化参数存在显著差异，为深入探究奶牛Ⅰ型酮病与Ⅱ型酮临床病理学、早期检测和诊断以及详细的发病机理提供依据，为今后有效地预防奶牛Ⅰ型、Ⅱ型酮病奠定基础。
본시험지재료해Ⅰ형、Ⅱ형동병발생시내우체내모사이화삼수적변화。재모집약화우장수궤선취산후7～28 d、평균태차위2～3태적시험내우，근거혈장중β-간정산（BHBA）、포도당（Glc）、유리지방산（NEFA）적함량이급림상발병특점분위Ⅰ형동병조（20두）、Ⅱ형동병조（20두）화건강대조조（10두）。결과현시，삼조간혈장중Glc、BH-BA、NEFA적농도여체황평분존재현저차이（P＜0.05），단삼조시험내우적비유량、산후천수、혈장중이도소（INS）함량피차간무현저성차이（P＞0.05）。Ⅰ형동병、Ⅱ형동병여건강대조조지간적이화삼수존재현저차이，위심입탐구내우Ⅰ형동병여Ⅱ형동림상병이학、조기검측화진단이급상세적발병궤리제공의거，위금후유효지예방내우Ⅰ형、Ⅱ형동병전정기출。
The objective is to investigate some biochemical parameters changes in type I and typeⅡ ketosis of dairy cows. The experimental cows with two or three parities were selected at 7~28 days postpartum in a intensive dairy farm. Cows were classified as type I ketotic (K1, 20 cows), type Ⅱ ketotic (K2, 20 cows), and healthy control group (C, 10 cows) based on the glucose (Glc) and 3-hydroxybutyrate acid (BHBA) levels and the clinical signs. The results revealed that body condition scores, Glc, BHBA and NEFA plasma levels were significantly different among three groups (P<0.05), however, the differences among the three groups in post-partum day, milk yield (MY), INS were not significant (P>0.05). Conclusion that some biochemical parameters were significantly different among type I ketosis, type Ⅱketosis and healthy control cows, thereby providing impor-tant information on the pathogenesis, early diagnosis, and prevention of type I and type Ⅱ keto-sis in dairy cows.