CAJ | 학술논문

目的：了解该院2012～2013年鲍曼不动杆菌的临床分布及其耐药情况，为临床的合理用药和医院感染的预防控制提供理论依据。方法回顾性分析2012年1月至2013年12月该院临床分离的205株鲍曼不动杆菌的药敏试验资料和各科分布情况资料。结果标本来源主要为痰液（88．7％），其次为分泌物（4．6％）。鲍曼不动杆菌的感染主要发生在急诊 ICU、外科ICU 及神经内科等科室。鲍曼不动杆菌对碳青霉烯类抗菌药物敏感率较高。多重耐药从2012年的47．2％下降到2013年的46．4％，泛耐药从2012年的33．3％下降到2013年的27．8％。结论鲍曼不动杆菌的多重耐药现象严重，对常用抗菌药物耐药率呈逐年上升趋势，临床应根据药敏试验结果合理使用抗菌药物。
목적：료해해원2012～2013년포만불동간균적림상분포급기내약정황，위림상적합리용약화의원감염적예방공제제공이론의거。방법회고성분석2012년1월지2013년12월해원림상분리적205주포만불동간균적약민시험자료화각과분포정황자료。결과표본래원주요위담액（88．7％），기차위분비물（4．6％）。포만불동간균적감염주요발생재급진 ICU、외과ICU 급신경내과등과실。포만불동간균대탄청매희류항균약물민감솔교고。다중내약종2012년적47．2％하강도2013년적46．4％，범내약종2012년적33．3％하강도2013년적27．8％。결론포만불동간균적다중내약현상엄중，대상용항균약물내약솔정축년상승추세，림상응근거약민시험결과합리사용항균약물。
Objective To understand the clinical distribution and drug resistance of Acinetobacter baumannii during 2012-2013 to provides the theoretical basis for clinical rational drug uses and the prevention and control of hospital infection.Methods To un-derstand the clinical distribution and drug resistance of Acinetobacter baumannii during 2012-2013 to provides the theoretical basis for clinical rational drug uses and the prevention and control of hospital infection.Results The main sources of specimens were sputum(88.7%),followed by secretions (4.6%).Acinetobacter baumannii infection occurred mainly in emergency ICU,surgical ICU,nerve internal medicine department,etc.Acinetobacter baumannii had the high sensitivity to carbapenem.Multiple drug resist-ance was decreased from 47.2% in 2012 to 46.4% in 2013,pan-drug resistance was decreased from 33.3% in 2012 to 27.8% in 2013.Conclusion Multiple drug resistance of Acinetobacter baumannii is serious,there is an upward trend in resistance to common-ly used antibacterial drugs,clinic should reasonably use antibacterial drugs based on the results of drug susceptibility test.