国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2014年
16期
2176-2178
,共3页
慢性肾功能不全%总铁结合力%维生素 B12
慢性腎功能不全%總鐵結閤力%維生素 B12
만성신공능불전%총철결합력%유생소 B12
chronic renal fail%total iron binding capacity%vitamin B12
目的：探讨慢性肾功能不全（CRF）患者血清铁（Fe）、总铁结合力（TIBC）、铁蛋白（SF）、叶酸（FA）和维生素 B12（ViB12）检测的临床诊疗价值。方法 ARCHITECT i2000SR 全自动免疫化学发光分析仪检测72例 CRF 患者和83例健康对照人群血清 SF、FA 和 ViB12水平；VITROS FS 5．1干式生化分析仪检测血清 Fe 和 TIBC 水平；Mindray BC-6800五分类血常规分析仪检测红细胞（RBC）、血红蛋白（HGB）、红细胞压积（HCT）和红细胞平均体积（MCV）。所有检测结果采用 SPSS16．0统计学软件进行统计分析。结果 CRF 患者 TIBC、RBC、HGB 和 HCT 均明显低于对照组（P ＜0．05）；SF 和 ViB12水平明显高于对照组（P ＜0．05）；血清 Fe 和 MCV 与对照组比较差异无统计学意义（P ＞0．05）；女性患者 FA 水平低于对照组（P ＜0．05），而男性患者FA 水平与对照组比较差异无统计学意义（P ＞0．05）。结论 CRF 患者体内贫血相关代谢物指标可为疾病的诊断和治疗提供一定的参考价值，对纠正肾功能不全引起的贫血有一定的指导意义。
目的：探討慢性腎功能不全（CRF）患者血清鐵（Fe）、總鐵結閤力（TIBC）、鐵蛋白（SF）、葉痠（FA）和維生素 B12（ViB12）檢測的臨床診療價值。方法 ARCHITECT i2000SR 全自動免疫化學髮光分析儀檢測72例 CRF 患者和83例健康對照人群血清 SF、FA 和 ViB12水平；VITROS FS 5．1榦式生化分析儀檢測血清 Fe 和 TIBC 水平；Mindray BC-6800五分類血常規分析儀檢測紅細胞（RBC）、血紅蛋白（HGB）、紅細胞壓積（HCT）和紅細胞平均體積（MCV）。所有檢測結果採用 SPSS16．0統計學軟件進行統計分析。結果 CRF 患者 TIBC、RBC、HGB 和 HCT 均明顯低于對照組（P ＜0．05）；SF 和 ViB12水平明顯高于對照組（P ＜0．05）；血清 Fe 和 MCV 與對照組比較差異無統計學意義（P ＞0．05）；女性患者 FA 水平低于對照組（P ＜0．05），而男性患者FA 水平與對照組比較差異無統計學意義（P ＞0．05）。結論 CRF 患者體內貧血相關代謝物指標可為疾病的診斷和治療提供一定的參攷價值，對糾正腎功能不全引起的貧血有一定的指導意義。
목적：탐토만성신공능불전（CRF）환자혈청철（Fe）、총철결합력（TIBC）、철단백（SF）、협산（FA）화유생소 B12（ViB12）검측적림상진료개치。방법 ARCHITECT i2000SR 전자동면역화학발광분석의검측72례 CRF 환자화83례건강대조인군혈청 SF、FA 화 ViB12수평；VITROS FS 5．1간식생화분석의검측혈청 Fe 화 TIBC 수평；Mindray BC-6800오분류혈상규분석의검측홍세포（RBC）、혈홍단백（HGB）、홍세포압적（HCT）화홍세포평균체적（MCV）。소유검측결과채용 SPSS16．0통계학연건진행통계분석。결과 CRF 환자 TIBC、RBC、HGB 화 HCT 균명현저우대조조（P ＜0．05）；SF 화 ViB12수평명현고우대조조（P ＜0．05）；혈청 Fe 화 MCV 여대조조비교차이무통계학의의（P ＞0．05）；녀성환자 FA 수평저우대조조（P ＜0．05），이남성환자FA 수평여대조조비교차이무통계학의의（P ＞0．05）。결론 CRF 환자체내빈혈상관대사물지표가위질병적진단화치료제공일정적삼고개치，대규정신공능불전인기적빈혈유일정적지도의의。
Objective To investigate the clinical value of serum iron(Fe),total iron binding capacity(TIBC),serum ferritin(SF), folic acid(FA)and vitamin 12(ViB12 )in the diagnosis and treatment of chronic renal failure(CRF).Methods Fasting blood sam-ples were collected from 72 patients with CRF and 83 normal controls.Then the serum SF,ViB12 and FA contents were measured by the ARCHITECT i2000SR fully automatic chemiluminescence immunoassay analyzer;serum Fe and TIBC were detected by the VITORS FS 5.1 dry biochemical analyzer;RBC,HGB,HCT and MCV were analyzed by the Mindray BC-6800 complete automated blood counter.The detection results were performed the statistical analysis by the SPSS16.0 software.Results The levels of TIBC,RBC,HGB and HCT in the CRF patients were significantly lower than those in the control group(P <0.05);while the SF and ViB12 levels were significantly higher than those in the control group;serum Fe and MCV had no statistical difference compared with the control group(P >0.05);the FA level in the female patients was lower than that in the control group,but which in the male patients had no statistical differences compared with the control group(P >0.05).Conclusion The indexes of anemia associat-ed metabolin in the CRF patients can provide certain reference value for the diagnosis and treatment of chronic renal fail and has cer-tain guidance significance for correcting anemia caused by renal insufficiency.
