国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2014年
16期
2154-2155,2158
,共3页
脑梗死%乳酸%B型钠尿肽%同型半胱氨酸
腦梗死%乳痠%B型鈉尿肽%同型半胱氨痠
뇌경사%유산%B형납뇨태%동형반광안산
acute cerebral infarction%lactic acid%natriuretic peptide%homocysteine
目的：探讨联合检测血乳酸、B 型钠尿肽（BNP）和同型半胱氨酸（Hcy）在老年急性脑梗死中的临床意义。方法采集该院收治的85例老年急性脑梗死患者急性发病期、溶栓术后24、48、72 h，禁食12 h 后的动、静脉血，分别检测血乳酸、BNP 和Hcy 水平，作动态监测分析研究，并与健康对照组进行对比观察。结果脑梗死患者急性发病期组、恢复期组血乳酸、BNP 和Hcy 水平均较健康对照组显著增高（P ＜0．05）。急性脑梗死组发病期血乳酸、BNP 和 Hcy 水平分别为（6．47±3．92）mmol/L、（100．52±48．96）pg/mL 和（28．87±15．13）μmol/L，明显高于脑梗死患者术后恢复期48～72 h 水平，差异有统计学意义（P ＜0．05），脑梗死组术后恢复期血乳酸、BNP 和 Hcy 水平逐渐下降，至术后72 h 血乳酸、BNP 和 Hcy 水平下降至最低，分别为（2．16±1．83）mmol/L、（33．61±10．42）pg/mL、（18．87±8．27）μmol/L。结论血乳酸、BNP 和 Hcy 与脑梗死的发生和发展密切相关，三项指标联合检测为老年急性脑梗死的早期诊断提供可靠依据，应及时对患者采取积极有效治疗，并进行动态监测，正确评估预后。
目的：探討聯閤檢測血乳痠、B 型鈉尿肽（BNP）和同型半胱氨痠（Hcy）在老年急性腦梗死中的臨床意義。方法採集該院收治的85例老年急性腦梗死患者急性髮病期、溶栓術後24、48、72 h，禁食12 h 後的動、靜脈血，分彆檢測血乳痠、BNP 和Hcy 水平，作動態鑑測分析研究，併與健康對照組進行對比觀察。結果腦梗死患者急性髮病期組、恢複期組血乳痠、BNP 和Hcy 水平均較健康對照組顯著增高（P ＜0．05）。急性腦梗死組髮病期血乳痠、BNP 和 Hcy 水平分彆為（6．47±3．92）mmol/L、（100．52±48．96）pg/mL 和（28．87±15．13）μmol/L，明顯高于腦梗死患者術後恢複期48～72 h 水平，差異有統計學意義（P ＜0．05），腦梗死組術後恢複期血乳痠、BNP 和 Hcy 水平逐漸下降，至術後72 h 血乳痠、BNP 和 Hcy 水平下降至最低，分彆為（2．16±1．83）mmol/L、（33．61±10．42）pg/mL、（18．87±8．27）μmol/L。結論血乳痠、BNP 和 Hcy 與腦梗死的髮生和髮展密切相關，三項指標聯閤檢測為老年急性腦梗死的早期診斷提供可靠依據，應及時對患者採取積極有效治療，併進行動態鑑測，正確評估預後。
목적：탐토연합검측혈유산、B 형납뇨태（BNP）화동형반광안산（Hcy）재노년급성뇌경사중적림상의의。방법채집해원수치적85례노년급성뇌경사환자급성발병기、용전술후24、48、72 h，금식12 h 후적동、정맥혈，분별검측혈유산、BNP 화Hcy 수평，작동태감측분석연구，병여건강대조조진행대비관찰。결과뇌경사환자급성발병기조、회복기조혈유산、BNP 화Hcy 수평균교건강대조조현저증고（P ＜0．05）。급성뇌경사조발병기혈유산、BNP 화 Hcy 수평분별위（6．47±3．92）mmol/L、（100．52±48．96）pg/mL 화（28．87±15．13）μmol/L，명현고우뇌경사환자술후회복기48～72 h 수평，차이유통계학의의（P ＜0．05），뇌경사조술후회복기혈유산、BNP 화 Hcy 수평축점하강，지술후72 h 혈유산、BNP 화 Hcy 수평하강지최저，분별위（2．16±1．83）mmol/L、（33．61±10．42）pg/mL、（18．87±8．27）μmol/L。결론혈유산、BNP 화 Hcy 여뇌경사적발생화발전밀절상관，삼항지표연합검측위노년급성뇌경사적조기진단제공가고의거，응급시대환자채취적겁유효치료，병진행동태감측，정학평고예후。
Objective To investigate the clinical significance of the combination detection of blood lactic acid,B-type brain natri-uretic peptide(BNP)and homocysteine(Hcy)in elderly acute cerebral infarction.Methods The arterial and venous blood during a-cute onset stage,at 24,48,72 h after thrombolysis and at 12 h after fasting in 85 cases of acute cerebral infarction was collected for detecting blood lactic acid,BNP and Hcy,performing the dynamic monitoring analysis and the comparative observation with the healthy control group.Results The blood lactic acid,BNP and Hcy levels in the acute onset stage group and the recovery group were significantly increased compared with the healthy control group(P <0.05).The blood lactic acid,BNP and Hcy levels during the onset stage in the acute cerebral infarction group were(6.47 ±3.92)mmol/L,(100.52 ±48.96 )pg/mL and(48.96 ±15.13 )μmol/L respectively,which were significantly higher than those at 48,72 h of postoperative recovery,the differences between them were statistically significant(P <0.05).The blood lactic acid,BNP and Hcy levels during postoperative convalescence in the cere-bral infarction group were gradually decreased and declined to the minimal level until postoperative 72 h,which were(2.16±1.83) mmol/L,(33.61±10.42)pg/mL and(18.87±8.27)μmol/L respectively.Conclusion Blood lactic acid,BNP and Hcy are closely related with the occurrence and development of cerebral infarction,the joint detection of these three indicators provide a reliable ba-sis for the early diagnosis of elderly acute cerebral infarction.The active and effective treatment on the patient should be timely a-dopted and the dynamic monitoring should be performed in order to correctly assess the prognosis.
