CAJ | 학술논문

目的：比较单纯翼状胬肉切除术与翼状胬肉切除术加自体角膜缘干细胞移植两种手术方式治疗原发性翼状胬肉的临床疗效。方法选择原发性翼状胬肉患者83例（92眼），A组41例（46眼）行单纯翼状胬肉切除术，术中应用丝裂霉素C；B组42例（46眼）行翼状胬肉切除加自体角膜缘干细胞移植。术后随访6~12个月，比较两组患者术后角膜创面愈合、角膜散光及复发情况。结果角膜荧光染色显示A组、B组角膜创面平均愈合时间分别为7.34 d和6.32 d，差异有统计学意义（ P﹤0.05）。术后3个月两组患者的角膜散光度比较差异无统计学意义（ P﹥0.05）。A组复发8眼（复发率为17.4%），B组2眼（复发率为4.3%），两组比较差异有统计学意义（ P﹤0.05）。结论翼状胬肉切除术加自体角膜缘干细胞移植手术方式优于单纯翼状胬肉切除术。
목적：비교단순익상노육절제술여익상노육절제술가자체각막연간세포이식량충수술방식치료원발성익상노육적림상료효。방법선택원발성익상노육환자83례（92안），A조41례（46안）행단순익상노육절제술，술중응용사렬매소C；B조42례（46안）행익상노육절제가자체각막연간세포이식。술후수방6~12개월，비교량조환자술후각막창면유합、각막산광급복발정황。결과각막형광염색현시A조、B조각막창면평균유합시간분별위7.34 d화6.32 d，차이유통계학의의（ P﹤0.05）。술후3개월량조환자적각막산광도비교차이무통계학의의（ P﹥0.05）。A조복발8안（복발솔위17.4%），B조2안（복발솔위4.3%），량조비교차이유통계학의의（ P﹤0.05）。결론익상노육절제술가자체각막연간세포이식수술방식우우단순익상노육절제술。
Objective To compare the clinical effects of Pterygium excision and autologous corneal limbal stem cell tran splantation combined with pterygium excision on primary pterygium. Methods Eighty-three patients(92 eyes) with primary pterygium were chose,41 patients(46 eyes)in group A were given simple pterygium excision,with MMC used during the operation,42 patients(46 eyes)in group B were given autologous corneal limbal stem cell transplantation com-bined with pterygium excision. The post-operative follow-up periods ranged from 6-12 months. The corneal wouds heal-ing,corneal astigmia and the recurrent rate of the two groups were compared. Results The average corneal wouds healing time was 7. 34 d in group A and 6. 32 d in group B,there was significant difference between the two groups( P﹤0. 05 ). There was no significant difference in the corneal astigmia degree between the two groups at 3 months after operation( P﹥0. 05). The recurrent rate was 17. 4%(8 eyes)in group A and 4. 3%(2 eyes)in group B,there was significant difference between the two groups( P﹤0. 05 ). Conclusions The method of pterygium excision combined with autologous corneal limbal stem cell transplantation is superior to single pterygium excision.