CAJ | 학술논문

目的：研究结核分枝杆菌特异性蛋白（ TB-SA）抗体用于结核病检测的价值。方法可疑结核病患者353例和健康志愿者74例同时进行结核分枝杆菌TB-SA抗体检测和结核菌素纯蛋白衍生物（ PPD）试验，并对可疑结核病患者进行痰涂片显微镜检查和分离培养鉴定。结果结核分枝杆菌TB-SA抗体检测菌阳肺结核的敏感度为87.92%（80/91）；诊断菌阴肺结核的敏感度为78.23%（194/248）；诊断结核病的总体敏感度为81.42%（276/339），特异度为86.36%（76/88）。结论结核分枝杆菌TB-SA抗体检测结核病有较好的敏感度和特异度，有利于结核病的辅助诊断和鉴别诊断。
목적：연구결핵분지간균특이성단백（ TB-SA）항체용우결핵병검측적개치。방법가의결핵병환자353례화건강지원자74례동시진행결핵분지간균TB-SA항체검측화결핵균소순단백연생물（ PPD）시험，병대가의결핵병환자진행담도편현미경검사화분리배양감정。결과결핵분지간균TB-SA항체검측균양폐결핵적민감도위87.92%（80/91）；진단균음폐결핵적민감도위78.23%（194/248）；진단결핵병적총체민감도위81.42%（276/339），특이도위86.36%（76/88）。결론결핵분지간균TB-SA항체검측결핵병유교호적민감도화특이도，유리우결핵병적보조진단화감별진단。
Objective To investigate the value of tuberculosis specific antigen( TB-SA)antibody on detecting tuberculosis. Methods The TB-SA antibody levels in the serum of 353 suspect tuberculosis and 74 healthy volunteers were detected by enzyme-linked immunosorbent assay. Tuberculosis was con-formed by clinic,bacteriology,X-ray examination. Results The sensitivity of TB-SA antibody in diag-nosis of bacteriolocally positive and negative pulmonary tuberculosis was 87. 92%( 80/91 )and 78. 23%(194/248 ),respectively;the combined sensitivity was 81. 42%( 276/339 ),and the specificity was 86. 36%(76/88). Conclusions TB-SA antibody has high sensitivity and specificity and is a good tool for detecting tuberculosis.