CAJ | 학술논문

目的：探讨16排C T全脑低采样灌注及血管成像在早期缺血性脑卒中的诊断价值。方法选择早期缺血性脑卒中患者60例，均接受CT灌注成像及CT血管造影检查。测量并比较梗死区、缺血半暗带区与对侧正常对照区CBV、CBF及MTT的不同，从CTA图像观察脑动脉狭窄情况。结果（1）脑梗死区CBF为（11.31±6.68）mL/（100g?min），显著低于缺血半暗带区及健侧对照区，MTT 为（17.46±4.85）s ，显著高于缺血半暗带区及健侧对照区，差异均有统计学意义（P＜0.05）。缺血半暗带区CBF低于健侧对照区，MTT长于健侧对照区，且CBV高于脑梗死区，差异均有统计学意义（P＜0.05）。（2）C T A共显示49例（81.7％）患者存在颅内动脉狭窄，其中颈内动脉系统狭窄30例，椎基底动脉系统狭窄13例，颈内动脉系及椎基底动脉系多发狭窄6例。结论16排C T全脑低采样灌注及血管成像可为早期缺血性脑卒中提供有价值的诊断信息，值得临床推广应用。
목적：탐토16배C T전뇌저채양관주급혈관성상재조기결혈성뇌졸중적진단개치。방법선택조기결혈성뇌졸중환자60례，균접수CT관주성상급CT혈관조영검사。측량병비교경사구、결혈반암대구여대측정상대조구CBV、CBF급MTT적불동，종CTA도상관찰뇌동맥협착정황。결과（1）뇌경사구CBF위（11.31±6.68）mL/（100g?min），현저저우결혈반암대구급건측대조구，MTT 위（17.46±4.85）s ，현저고우결혈반암대구급건측대조구，차이균유통계학의의（P＜0.05）。결혈반암대구CBF저우건측대조구，MTT장우건측대조구，차CBV고우뇌경사구，차이균유통계학의의（P＜0.05）。（2）C T A공현시49례（81.7％）환자존재로내동맥협착，기중경내동맥계통협착30례，추기저동맥계통협착13례，경내동맥계급추기저동맥계다발협착6례。결론16배C T전뇌저채양관주급혈관성상가위조기결혈성뇌졸중제공유개치적진단신식，치득림상추엄응용。
Objective To investigate the application value of 16 slice CT low sampling perfusion and angiography imaging in the early stage of cerebral infarction. Methods Sixty patients with ischemic stroke were selected ,CT perfusion and CTA were performed for them using 16 slice CT ,the CBF ,CBV and MTT values of each ROI were compared ,the stenosis of cere-bral arteries were observed. Results CBF in infarction area was (11.31 ± 6.68) mL/(100g?min) ,significantly lower than that in the ischemic penumbra and contralateral area ,MTT was (17.46 ± 4.85) s ,significantly higher than that in the ischemic penumbra band and that in contralateral control area ,the differences were statistically significant (P<0.05). CBF in Ischemic penumbra was lower than that in the contralateral area ,MTT was longer than that in the contralateral control area ,and CBV in Ischemic penumbra was bigger than that in cerebral infarction area ,and the differences were statistically significant (P<0.05) . CTA showed that 49 patients were afflicted with intracranial arterial stenosis ,the ratio was 81.7% ,30 cases of with internal carotid artery stenosis ,13 cases with vertebral artery-basilar artery stenosis ,6 cases with multiple stenosis in internal carotid artery system and vertebral artery-basilar artery.16-slice CT low sampling perfusion and cerebral angiography for early ischemic stroke can provide valuable diagnostic information ,and is worthy of clinical application.