CAJ | 학술논문

目的：探讨尼莫地平对高血压脑出血患者围术期血流动力学的影响。方法选取我院2012-01-2012-06收治的88例高血压脑出血患者为研究对象。按照入院顺序随机分为治疗组与对照组。治疗组围术期应用尼莫地平治疗，对照组围术期应用乌拉地尔治疗。对比2组围术期血流变化情况。结果手术后3d，治疗组患者的平均血流量与平均血流速度显著高于对照组，外周阻力与临界压力显著低于对照组，差异具有统计学意义（P＜0.05）。结论尼莫地平在高血压脑出血患者的围术期治疗中，脑血流量显著增大，脑血管阻力减小，对于患者术后的血压控制效果显著，值得临床推广应用。
목적：탐토니막지평대고혈압뇌출혈환자위술기혈류동역학적영향。방법선취아원2012-01-2012-06수치적88례고혈압뇌출혈환자위연구대상。안조입원순서수궤분위치료조여대조조。치료조위술기응용니막지평치료，대조조위술기응용오랍지이치료。대비2조위술기혈류변화정황。결과수술후3d，치료조환자적평균혈류량여평균혈류속도현저고우대조조，외주조력여림계압력현저저우대조조，차이구유통계학의의（P＜0.05）。결론니막지평재고혈압뇌출혈환자적위술기치료중，뇌혈류량현저증대，뇌혈관조력감소，대우환자술후적혈압공제효과현저，치득림상추엄응용。
Objective To observe the influence of nimodipine on haemodynamics in the perio-perative period of patients with hypertensive intracerebral hemorrhage .Methods 88 patients with hypertensive intracerebral hemorrhage in our hospital from January 2012 to June 2012 were randomly divided into the treatment group (treated with nimodipine) and the control group (treated with urapidil) .The perioperative period haemodynamics of two groups were compared .Results 3d after opera-tion ,the average blood flow and average blood velocity in the treatment group were higher than these in the control group ,and the peripheral resistance and critical pressure in the treatment group were lower than these in the control group .Conclusion Nimodipine can increase the average blood flow and velocity and decrease the peripheral resistance and critical pressure to pa-tients with hypertensive intracerebral hemorrhage .