CAJ | 학술논문

目的：观察灯盏花素联合前列地尔治疗急性脑梗死患者的临床疗效及对血液流变学的影响。方法90例急性脑梗死患者按照治疗方法不同分为治疗组47例与对照组43例，对照组给予常规药物治疗，治疗组在基础上加用灯盏花素、前列地尔治疗，连续治疗14 d后比较2组临床疗效及对血液流变学的影响。结果治疗组总有效率明显高于对照组（χ2＝11.260，P＝0.007），治疗后全血高切、低切、红细胞比积、血浆黏度、纤维蛋白原等指标均较治疗前、同期对照组改善明显，差异具有统计学意义（P＜0.05）。结论灯盏花素联合前列地尔治疗急性脑梗死可提高治疗效果，其可能通过改变血液流变学发挥作用。
목적：관찰등잔화소연합전렬지이치료급성뇌경사환자적림상료효급대혈액류변학적영향。방법90례급성뇌경사환자안조치료방법불동분위치료조47례여대조조43례，대조조급여상규약물치료，치료조재기출상가용등잔화소、전렬지이치료，련속치료14 d후비교2조림상료효급대혈액류변학적영향。결과치료조총유효솔명현고우대조조（χ2＝11.260，P＝0.007），치료후전혈고절、저절、홍세포비적、혈장점도、섬유단백원등지표균교치료전、동기대조조개선명현，차이구유통계학의의（P＜0.05）。결론등잔화소연합전렬지이치료급성뇌경사가제고치료효과，기가능통과개변혈액류변학발휘작용。
Objective To investigate the curative effect and hemorheology of breviscapine combined with alprostadil trea-ting patients with acute cerebral infarction .Methods 90 patients with acute cerebral infarction were divided into the treatment group (n=47 ,treated with breviscapine plus alprostadil combined with conventional medicine )and the control group (n=43 , treated with conventional medicine) .The curative effect and hemorheology of two groups were compared after continuous 14d treatment .Results The total effective rate of treatment group was higher than that of the control group .The high blood vis-cosity ,low cut ,hematocrit ,plasma viscosity and fibrinogen of treatment group were more than these of control group ,which had statistical significance .Conclusion Breviscapine combined with alprostadil can increase the curative effect of patients with acute cerebral infarction ,which can be achieved by changing hemorheology .