CAJ | 학술논문

目的：探讨ABCD2评分与LDL-C联合用于短暂性脑缺血发作（T IA ）患者短期脑卒中风险预测中的临床价值。方法112例TIA患者根据是否发生早期脑梗死分为脑梗死组（n＝28）与非脑梗死组（n＝84），对比2组患者ABCD2评分、LDL-C水平；根据患者LDL-C水平分为LDL-C≤3.1 mmol/L（n＝78）组及LDL-C＞3.1 mmol/L组（n＝34），对比2组早期脑梗死发生率；根据2组ABCD2＋LDL-C综合评分进行危险分层（低危组50例，中危组47例，高危组15例），对比不同层级患者脑梗死发生率。结果脑梗死组ABCD2评分、LDL-C水平以及ABCD2＋ LDL-C综合评分均显著高于非脑梗死组（ P＜0.01）；低危组患者脑梗死发生率显著低于中危组（P＜0.01），中危组显著低于高危组（P＜0.01）；LDL-C＜3.1 mmol/L组脑梗死发生率显著低于LDL-C≥3.1 mmol/L组（P＜0.01）。结论 ABCD2评分及LDL-C水平检测均能够进行TIA患者早期脑梗死风险，但二者联合应用临床价值更高。
목적：탐토ABCD2평분여LDL-C연합용우단잠성뇌결혈발작（T IA ）환자단기뇌졸중풍험예측중적림상개치。방법112례TIA환자근거시부발생조기뇌경사분위뇌경사조（n＝28）여비뇌경사조（n＝84），대비2조환자ABCD2평분、LDL-C수평；근거환자LDL-C수평분위LDL-C≤3.1 mmol/L（n＝78）조급LDL-C＞3.1 mmol/L조（n＝34），대비2조조기뇌경사발생솔；근거2조ABCD2＋LDL-C종합평분진행위험분층（저위조50례，중위조47례，고위조15례），대비불동층급환자뇌경사발생솔。결과뇌경사조ABCD2평분、LDL-C수평이급ABCD2＋ LDL-C종합평분균현저고우비뇌경사조（ P＜0.01）；저위조환자뇌경사발생솔현저저우중위조（P＜0.01），중위조현저저우고위조（P＜0.01）；LDL-C＜3.1 mmol/L조뇌경사발생솔현저저우LDL-C≥3.1 mmol/L조（P＜0.01）。결론 ABCD2평분급LDL-C수평검측균능구진행TIA환자조기뇌경사풍험，단이자연합응용림상개치경고。
Objective To discuss the clinical significance of ABCD2 score combined with LDL-C in stroke risk prediction in patients with TIA .Methods Totally 112 patients with TIA were divided into the cerebral infarction group (n=28) and the non-cerebral infarction group(n=84) depending on whether cerebral infarction occurred within 7days ,ABCD2 score and LDL-C were contrasted between the two groups ;and Patients were divided into LDL-C≤3.1 mmol/L group(n=78) and LDL-C>3.1 mmol/L group(n=34) according to the LDL-C levels ,then the incidence of cerebral infarction were contrasted ;and the in-cidence of cerebral infarction were contrasted in different risk stratification (50 cases of low-risk group ,middle-risk group 47 cases ,15 cases of high-risk group) patients based on ABCD2+LDL-C composite score .Results ABCD2 score ,LDL-C level , and ABCD2+LDL-C composite score were significantly higher in the cerebral infarction group than those in the non-cerebral in-farction group(P<0.01);the incidence of cerebral infarction of the high-risk group was significantly higher than that of the middle-risk group(P<0.01) ,and significantly higher than that in the low-risk group(P<0.01);The incidence of cerebral in-farction in the LDL-C<3.1 mmol/L group was significantly lower than that of the LDL-C≥3.1 mmol/L group(P<0.01). Conclusion ABCD2 score and LDL-C levels are all able to predict the risk of cerebral infarction in patients with TIA ,but the combination of both has a higher meaning.