中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2014年
18期
3-4
,共2页
新生儿心肌损伤%磷酸肌酸钠%临床分析
新生兒心肌損傷%燐痠肌痠鈉%臨床分析
신생인심기손상%린산기산납%림상분석
Newborn's myocardial damage%Creatine phosphate sodium%Clinical analysis
目的：探讨磷酸肌酸钠治疗新生儿心肌损伤的临床分析。方法选择2011年12月-2013年9月，该院儿科收治的79例新生儿心肌损伤患儿随机分为试验组40例和对照组39例，两组均采取相同的治疗方案，试验组在相同治疗方案基础上加用注射用磷酸肌酸钠，比较两组治疗前后心肌酶谱、ECG变化。结果磷酸肌酸钠治疗7 d后患儿心肌酶谱[肌酸激酶( CK)424.1±61.1肌酸激酶同工酶( CK-MB)45.0±23.9乳酸脱氢酶(LDH)238±135羟丁酸脱氢酶( HBDH)67.5±141.2]较之前均有明显下降，差异有统计学意义(P＜0.05)，试验组显效率65.0%和总有效率90%均高于对照组差异有统计学意义(P＜0.05)。结论磷酸肌酸钠治疗新生儿心肌损伤疗效显著，且能对新生儿心肌损伤具有保护、促进心肌组织及心功能恢复的作用，值得临床推广。
目的：探討燐痠肌痠鈉治療新生兒心肌損傷的臨床分析。方法選擇2011年12月-2013年9月，該院兒科收治的79例新生兒心肌損傷患兒隨機分為試驗組40例和對照組39例，兩組均採取相同的治療方案，試驗組在相同治療方案基礎上加用註射用燐痠肌痠鈉，比較兩組治療前後心肌酶譜、ECG變化。結果燐痠肌痠鈉治療7 d後患兒心肌酶譜[肌痠激酶( CK)424.1±61.1肌痠激酶同工酶( CK-MB)45.0±23.9乳痠脫氫酶(LDH)238±135羥丁痠脫氫酶( HBDH)67.5±141.2]較之前均有明顯下降，差異有統計學意義(P＜0.05)，試驗組顯效率65.0%和總有效率90%均高于對照組差異有統計學意義(P＜0.05)。結論燐痠肌痠鈉治療新生兒心肌損傷療效顯著，且能對新生兒心肌損傷具有保護、促進心肌組織及心功能恢複的作用，值得臨床推廣。
목적：탐토린산기산납치료신생인심기손상적림상분석。방법선택2011년12월-2013년9월，해원인과수치적79례신생인심기손상환인수궤분위시험조40례화대조조39례，량조균채취상동적치료방안，시험조재상동치료방안기출상가용주사용린산기산납，비교량조치료전후심기매보、ECG변화。결과린산기산납치료7 d후환인심기매보[기산격매( CK)424.1±61.1기산격매동공매( CK-MB)45.0±23.9유산탈경매(LDH)238±135간정산탈경매( HBDH)67.5±141.2]교지전균유명현하강，차이유통계학의의(P＜0.05)，시험조현효솔65.0%화총유효솔90%균고우대조조차이유통계학의의(P＜0.05)。결론린산기산납치료신생인심기손상료효현저，차능대신생인심기손상구유보호、촉진심기조직급심공능회복적작용，치득림상추엄。
Objective To explore the clinical curative effect of creatine phosphate sodium in the treatment of myocardial damage in newborns. Methods 79 neonates with newborn's myocardial damage admitted in Department of Pediatrics of our hospital from December, 2011 to December, 2013 were selected and randomly divided into the experimental group (n=40) and the control group (n=39). Both groups were given the same therapeutic regimen, in addition, the experimental group was given creatine phosphate sodium for injection. The changes of myocardial enzyme spectrum and ECG before and after the treatment of the two groups were compared. Results After 7 days of treatment, the children's myocardial enzyme spectrum [(creatine kinase(CK) 424.1±61.1, crea-tine kinase isoenzyme(CK-MB) 45.0±23.9, lactate dehydrogenase(LDH) 238±135, hydroxybutyrate dehydrogenase( HBDH) 67.5± 141.2]decreased significantly as compare with that before treatment (P<0.05);the marked improvement rate and the total effective rate of the experimental group was 65.0%and 90%, respectively, which was higher than that of the control group, respectively (P<0.05). Conclusion Creatine phosphate sodium has significant effect in treatment of newborn's myocardial damage, which can pro-tect the newborn's myocardial damage, promote the recovery of myocardial tissue and cardiac function, and is worthy of clinical promotion.
