CAJ | 학술논문

目的：探讨慢性期脑梗死锥体束华勒氏变性（ WD）的磁共振诊断价值。方法搜集单侧大脑半球病变的继发WD患者20例，均行常规MRI（T1WI、T2WI、FLAIR）及DWI功能成像。结果 WD表现为单侧大脑半球陈旧性脑梗死，并出现不同程度的继发性表现，沿锥体束走行并与原发病灶相连或不相连的斑片状等T1、长T2异常信号，FLAIR中央低信号，边缘高信号（20例）；另7例合并患侧大脑脚、桥脑萎缩。结论 MRI能准确反映中枢神经WD系由神经元近端损伤累及远段轴突和髓鞘的顺行性变性的原发和继发性变性病变的特征性改变，从而提高对该变性的认识，提高诊断准确性。
목적：탐토만성기뇌경사추체속화륵씨변성（ WD）적자공진진단개치。방법수집단측대뇌반구병변적계발WD환자20례，균행상규MRI（T1WI、T2WI、FLAIR）급DWI공능성상。결과 WD표현위단측대뇌반구진구성뇌경사，병출현불동정도적계발성표현，연추체속주행병여원발병조상련혹불상련적반편상등T1、장T2이상신호，FLAIR중앙저신호，변연고신호（20례）；령7례합병환측대뇌각、교뇌위축。결론 MRI능준학반영중추신경WD계유신경원근단손상루급원단축돌화수초적순행성변성적원발화계발성변성병변적특정성개변，종이제고대해변성적인식，제고진단준학성。
Objective To analyze the MR findings of Wallerian degeneration in pyramidal tract,so as to improve the diagnosis accuracy. Methods Twenty cases of Wallerian degeneration in pyramidal tract were analyzed by MR,with T1WI,T2WI,FLAIR and DWI. Results A total of 20 cases of Wrallerian degeneration in pyramidal tract showed unilat-eral pulmonary cerebral infarction cerebral hemisphere,and with secondary findings,including cerebral peduncle and pons atrophy(7 cases),or the long T1/T2 signal and high signal in FLAIR along the pyramidal tract. Conclusions MRI can show the morphological changes from neurons to axons and myelin sheath in Wallerian degeneration correctly,and it is valu-able in the diagnosis of Wallerian degeneration in pyramidal tract.