CAJ | 학술논문

目的：探索针刺风府穴对紧张型头痛大鼠张颌反射波幅和潜伏期的影响。方法采用大鼠双侧半棘肌注射三磷酸腺苷二钠注射液(ATP)的方法制备紧张型头痛大鼠模型。体重220~260 g的SPF级Wistar大鼠40只，雌雄各半，分为空白组、模型组、风府穴组和假穴组四组，通过定量分析紧张型头痛模型大鼠张颌反射波幅及潜伏期，反映头颈部皮肤肌肉筋膜痛阈及敏感性变化。结果空白组半棘肌注射生理盐水不引起张颌反射波幅及潜伏期变化(P>0.05)；模型组半棘肌注射ATP导致张颌反射波幅下降(P<0.05)，潜伏期见缩短趋势，但差异无统计学意义(P>0.05)；针刺风府穴可见风府穴组JOR波幅升高(P<0.05)，潜伏期延长(P<0.05)；针刺假穴见张颌反射波幅升高(P<0.05)，潜伏期延长，但差异无统计学意义(P>0.05)。与模型组相比，风府穴组波幅明显升高(P<0.01)，假穴组差异无统计学意义(P>0.05)；风府穴组波幅较假穴组升高明显(P<0.01)。与模型组相比，风府穴组潜伏期明显延长(P<0.01)，假穴组差异无统计学意义(P>0.05)；风府穴组潜伏期与假穴组相比差异无统计学意义(P>0.05)。结论针刺风府穴可提高张颌反射波幅，延长潜伏期，即提高痛阈，降低头颈部肌筋膜敏感性。
목적：탐색침자풍부혈대긴장형두통대서장합반사파폭화잠복기적영향。방법채용대서쌍측반극기주사삼린산선감이납주사액(ATP)적방법제비긴장형두통대서모형。체중220~260 g적SPF급Wistar대서40지，자웅각반，분위공백조、모형조、풍부혈조화가혈조사조，통과정량분석긴장형두통모형대서장합반사파폭급잠복기，반영두경부피부기육근막통역급민감성변화。결과공백조반극기주사생리염수불인기장합반사파폭급잠복기변화(P>0.05)；모형조반극기주사ATP도치장합반사파폭하강(P<0.05)，잠복기견축단추세，단차이무통계학의의(P>0.05)；침자풍부혈가견풍부혈조JOR파폭승고(P<0.05)，잠복기연장(P<0.05)；침자가혈견장합반사파폭승고(P<0.05)，잠복기연장，단차이무통계학의의(P>0.05)。여모형조상비，풍부혈조파폭명현승고(P<0.01)，가혈조차이무통계학의의(P>0.05)；풍부혈조파폭교가혈조승고명현(P<0.01)。여모형조상비，풍부혈조잠복기명현연장(P<0.01)，가혈조차이무통계학의의(P>0.05)；풍부혈조잠복기여가혈조상비차이무통계학의의(P>0.05)。결론침자풍부혈가제고장합반사파폭，연장잠복기，즉제고통역，강저두경부기근막민감성。
Objective To explore the influence of acupuncturing Feng-fu acupoint on amplitude and latency of jaw-opening reflex (JOR) of rats with tension-type headache (TTH). Methods The TTH rat model was prepared by injecting ATP into rats' bilateral semispinalis capitis. 40 SPF-Wistar rats weighting 220-260 g, half male and half female, were divided into four groups: blank group, model group, Feng-fu acupoint group and non-acpoint group. Change of pain threshold and sensitivity of muscle and fascia in head and neck was observed by making quantitative analysis on JOR amplitude and latency of TTH model rats. Results No change of JOR's amplitude and latency was caused in blank group with NS injected into semispinalis capitis (P>0.05), JOR's amplitude was decreased in model group with ATP in-jected (P<0.05) and the shortened tendency of its latency was not significant (P>0.05), JOR's amplitude was increased and latency was shortened in Feng-fu acupoint group, JOR's amplitude was increased in non-acupoint group (P<0.05) and the extended tendency of its latency was not significant (P> 0.05). Compared with model group, JOR's amplitude and latency of Feng-fu acupoint group were increased remarkably (P<0.01), by contrast, non-acupoint group had no significant difference (P> 0.05). Compared with non-acupoint group, JOR's amplitude of Feng-fu acupoint group was increased observably (P< 0.01), while latency was not (P> 0.05). Conclusion Acupuncturing Feng-fu acupoint could increase JOR's amplitude and extend its latency, in oth-er words, it can increase pain threshold and decrease sensitivity of muscle and fascia in head and neck.