CAJ | 학술논문

目的：观察十全大补汤联合 GP 方案治疗晚期非小细胞肺癌的临床疗效。方法将62例晚期肺癌患者随机分成两组各31例，对照组采用 GP 方案（吉西他滨1000 mg/ m2，第1、8天静脉滴注，顺铂60 mg/ m3第1天静脉滴注）治疗，治疗组予十全大补汤联合 GP 方案治疗，化疗至少3个周期。结果两组在提高免疫功能，减轻化疗毒性、降低 VEGF 与 CYFRA21-1、临床症状积分、KPS 评分上比较差异均有统计学意义（P ﹤0.05）。结论十全大补汤联合 GP 方案可以增强晚期非小细胞肺癌的免疫功能、减毒增效及提高患者生活质量。
목적：관찰십전대보탕연합 GP 방안치료만기비소세포폐암적림상료효。방법장62례만기폐암환자수궤분성량조각31례，대조조채용 GP 방안（길서타빈1000 mg/ m2，제1、8천정맥적주，순박60 mg/ m3제1천정맥적주）치료，치료조여십전대보탕연합 GP 방안치료，화료지소3개주기。결과량조재제고면역공능，감경화료독성、강저 VEGF 여 CYFRA21-1、림상증상적분、KPS 평분상비교차이균유통계학의의（P ﹤0.05）。결론십전대보탕연합 GP 방안가이증강만기비소세포폐암적면역공능、감독증효급제고환자생활질량。
Objective To observe the clinical efficacy of Shiquandabu decoction combined with gemcitabine-cipla-timon(GP)regimen on advanced non-small cell lung cancer( NSCLC). Methods Sixty-two patients with advanced NSCLC were randomly divided into two groups,with 31 cases in each group. The control group was treated with GP regimen, the treatment group was treated with Shiquandabu decoction combined with GP program. A treatment cycle lasted for 21 days and patients recieved chemotherapy for at least three cycles. Results There was significant difference between the two groups in improving the immune function,reducing toxicity of chemotherapy,and the changes of VEGF and CYFRA21-1 levels in peripheral blood,KPS scores,clinical scores(P ﹤ 0. 05). Conclusions Shiquandabu decoction combined with GP program can enhance the immune function,reduce toxicity of chemotherapy and increase efficiency and improve the quality of life of advanced non-small cell lung cancer patients.