医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2014年
23期
260-260
,共1页
氯吡格雷%不稳定型心绞痛%观察
氯吡格雷%不穩定型心絞痛%觀察
록필격뢰%불은정형심교통%관찰
Clopidogrel%Unstable angina pectoris%Observation
目的：研究应用氯吡格雷治疗不稳定型心绞痛临床效果。方法不稳定型心绞痛患者100例,随机分为对照组和治疗组各50例,均给予口服阿司匹林100mg/d,皮下注射低分子肝素钙5000u/12h。治疗组另给予氯吡格雷75mg/d,疗程3w,治疗开始前及结束后分别测量高敏性C反应蛋白,每天观察患者心绞痛发作次数、持续时间、记录心电图。结果治疗组总有效率为98.00%,高于对照组的总有效率82%,心血管疾病发生率治疗组低于对照组,治疗组疗效优于对照组,差异有显著性,P<0.05；两组血清高敏性C反应蛋白水平比较：治疗前两组C反应蛋白水平差异不显著,P>0.05。治疗后对照组高于治疗组,差异显著,P<0.01。两组治疗后与治疗前相比C反应蛋白水平均降低,差异有显著性,P<0.05。结论氯吡格雷治疗不稳定型心绞痛可以明显减轻急性期症状,并降低心肌梗死等严重心血管疾病的风险,值得临床推广。
目的：研究應用氯吡格雷治療不穩定型心絞痛臨床效果。方法不穩定型心絞痛患者100例,隨機分為對照組和治療組各50例,均給予口服阿司匹林100mg/d,皮下註射低分子肝素鈣5000u/12h。治療組另給予氯吡格雷75mg/d,療程3w,治療開始前及結束後分彆測量高敏性C反應蛋白,每天觀察患者心絞痛髮作次數、持續時間、記錄心電圖。結果治療組總有效率為98.00%,高于對照組的總有效率82%,心血管疾病髮生率治療組低于對照組,治療組療效優于對照組,差異有顯著性,P<0.05；兩組血清高敏性C反應蛋白水平比較：治療前兩組C反應蛋白水平差異不顯著,P>0.05。治療後對照組高于治療組,差異顯著,P<0.01。兩組治療後與治療前相比C反應蛋白水平均降低,差異有顯著性,P<0.05。結論氯吡格雷治療不穩定型心絞痛可以明顯減輕急性期癥狀,併降低心肌梗死等嚴重心血管疾病的風險,值得臨床推廣。
목적：연구응용록필격뢰치료불은정형심교통림상효과。방법불은정형심교통환자100례,수궤분위대조조화치료조각50례,균급여구복아사필림100mg/d,피하주사저분자간소개5000u/12h。치료조령급여록필격뢰75mg/d,료정3w,치료개시전급결속후분별측량고민성C반응단백,매천관찰환자심교통발작차수、지속시간、기록심전도。결과치료조총유효솔위98.00%,고우대조조적총유효솔82%,심혈관질병발생솔치료조저우대조조,치료조료효우우대조조,차이유현저성,P<0.05；량조혈청고민성C반응단백수평비교：치료전량조C반응단백수평차이불현저,P>0.05。치료후대조조고우치료조,차이현저,P<0.01。량조치료후여치료전상비C반응단백수평균강저,차이유현저성,P<0.05。결론록필격뢰치료불은정형심교통가이명현감경급성기증상,병강저심기경사등엄중심혈관질병적풍험,치득림상추엄。
Objective To study the treatment of unstable anginaclopidogrel clinical ef ect.Methods 100 patients with unstable angina were randomly divided into a control group and the treatment group,50 patients were given aspirin 100mg/d,subcutaneous low molecular weight heparin 5000U/12h.Another clopidogrel treatment groups 75mg/d,for3weeks,were measured before and after the start of treatment of high sensitivity C -reactive protein were observed in patients with angina at ack frequency, duration, daily ECG recording . Results The total ef ective rate was 98.00%,higher than the total ef iciency of 82%,the incidence of cardiovascular disease treatment group than the control group,the treatment group than the control group, the dif erence was significant, <0.05;levels of serum high- sensitivity C-reactive protein level comparison:before treatment C-reactive protein level was not significant, >0.05.Treatment group than in the control treatment group,the dif erence was significant, <0.01.Reactive protein C compared with pre-treatment mean decrease after treatment,the dif erence was significant, <0.05. Conclusion The treatment of unstable angina clopidogrel can significantly reduce acute symptoms and reduce the risk of serious cardiovascular disease,such as myocardial infarction,worthy of promotion.
