CAJ | 학술논문

目的：比较微量泵输注与静脉注射氯解磷定抢救有机磷农药中毒患者的临床效果。方法回顾性分析84例急性有机磷农药中毒病例，按照随机对照原则分为A、B两组。 A组患者采用常规间断静脉注射氯解磷定；B组在首次静脉注射氯解磷定后给予持续微量泵静脉维持给药。观察比较两组患者的胆碱酯酶恢复情况、住院时间、不良反应发生率、及死亡率。结果 B组患者的胆碱酯酶恢复时间(P<0.001)、住院时间(P<0.01)、不良反应发生率及死亡率(P<0.005)均低于A组。结论微量泵输注氯解磷定抢救有机磷中毒死亡率及不良反应发生率低，并且操作简便，值得临床推广。
목적：비교미량빙수주여정맥주사록해린정창구유궤린농약중독환자적림상효과。방법회고성분석84례급성유궤린농약중독병례，안조수궤대조원칙분위A、B량조。 A조환자채용상규간단정맥주사록해린정；B조재수차정맥주사록해린정후급여지속미량빙정맥유지급약。관찰비교량조환자적담감지매회복정황、주원시간、불량반응발생솔、급사망솔。결과 B조환자적담감지매회복시간(P<0.001)、주원시간(P<0.01)、불량반응발생솔급사망솔(P<0.005)균저우A조。결론미량빙수주록해린정창구유궤린중독사망솔급불량반응발생솔저，병차조작간편，치득림상추엄。
Objettive To compare The clinical ef ect of patients with acute Organophosphate poisoning treated by pralidoxime Chloride using intravenous injection and micro pump. Methods 84 patients with acute Organophosphate poisoning were retrospectively analyzed. The patients were divided into group A and group B. Each group has 42 cases. patients in group A were treated with intermit ent intravenous injection of Pralidoxime Chloride. patients in group B were treated with continuous intravenous injection of Pralidoxime Chloride by micro pump. The recovery of cholinesterase, average length of stay in hospital ,the incidence of adverse reactions, mortality rate were compared between the two groups. Rusults The recovery time of cholinesterase ( P<0.001), average length of stay ( P<0.01), incidence of adverse reactions and mortality rate ( P<0.005).in group B were significantly less than those in group A. Conclusion Mortality rate and incidence of adverse reactions of patients with acute Organophosphate poisoning treated by cholinesterase Chloride using micro pump is less, and it is easy to control, it is worthy of clinical application.