CAJ | 학술논문

目的：探讨胃癌根治术后影响患者预后的多因素。方法选取2004年1月~2008年1月我院收治的胃癌根治术患者60例,采用Kaplan-Meier法计算患者生存率,采用Log-rank法对影响胃癌患者的预后因素进行单因素分析,应用COX模型对影响胃癌患者的预后因素进行多因素回归分析。结果性别、年龄、手术方式对胃癌根治术后患者的生存率无明显影响(>0.05),Borrmann分型、组织学类型、TNM分期、浸润情况、淋巴结转移为影响胃癌根治术患者预后的相关因素(<0.05)。Cox多因素回归分析表明,Borrmann分型、TNM分期、浸润情况、淋巴结转移程度为影响胃癌根治术患者预后的独立危险因素(<0.05),其中组织学分型OR值最大(OR=2.942),表明相关性最强。结论组织学分型、淋巴结转移、肿瘤浸润深度是影响胃癌根治术患者预后的独立因素,综合评估以上影响因素可以为胃癌患者术后治疗、评估预后和复发转移提供指导依据,从而采取相应的防治措施,降低复发率,改善患者预后。
목적：탐토위암근치술후영향환자예후적다인소。방법선취2004년1월~2008년1월아원수치적위암근치술환자60례,채용Kaplan-Meier법계산환자생존솔,채용Log-rank법대영향위암환자적예후인소진행단인소분석,응용COX모형대영향위암환자적예후인소진행다인소회귀분석。결과성별、년령、수술방식대위암근치술후환자적생존솔무명현영향(>0.05),Borrmann분형、조직학류형、TNM분기、침윤정황、림파결전이위영향위암근치술환자예후적상관인소(<0.05)。Cox다인소회귀분석표명,Borrmann분형、TNM분기、침윤정황、림파결전이정도위영향위암근치술환자예후적독립위험인소(<0.05),기중조직학분형OR치최대(OR=2.942),표명상관성최강。결론조직학분형、림파결전이、종류침윤심도시영향위암근치술환자예후적독립인소,종합평고이상영향인소가이위위암환자술후치료、평고예후화복발전이제공지도의거,종이채취상응적방치조시,강저복발솔,개선환자예후。
Objective To investigate the ef ects of gastric cancer prognostic factors of postoperative cure.Methods From January 2004 to January 2008,60 cases of gastric cancer patients in our hospital radical mastectomy,calculated using the Kaplan-Meier method survival rate of patients,used Log-rank method for prognostic factors in patients with gastric cancer univariate analysis application,COX model prognostic factors in patients with gastric cancer multivariate regression analysis.Results Gender, age,surgical cure for stomach cancer patients had no ef ect on survival ( >0.05),Borrmann type,histological type,TNM stage,infiltration,lymph node metastasis affecting the prognosis of patients with gastric cancer surgery related factors ( <0.05).Cox multivariate regression analysis showed that,Borrmann type,TNM stage,infiltration,lymph node metastasis of gastric cancer were independent risk factors af ecting the prognosis of patients ( <0.05),in which the maximum value of histological type OR (OR=2.942), showed the strongest correlation.Conclusion The histological type,lymph node metastasis,depth of tumor invasion is an independent prognostic factor in gastric cancer surgery impact,comprehensive assessment of the above factors can treat gastric cancer patients after surgery,prognosis and recurrence basis to provide guidance,in order to take appropriate prevention measures to reduce the relapse rate,improve patient prognosis.