中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2014年
35期
5666-5670
,共5页
陈荣国%代凤雷%欧先锋%杨超%钱建吉%曾怿%任家云%虞泽龙
陳榮國%代鳳雷%歐先鋒%楊超%錢建吉%曾懌%任傢雲%虞澤龍
진영국%대봉뢰%구선봉%양초%전건길%증역%임가운%우택룡
植入物%脊柱植入物%椎弓根螺钉%腰椎退变%骨水泥%骨质疏松
植入物%脊柱植入物%椎弓根螺釘%腰椎退變%骨水泥%骨質疏鬆
식입물%척주식입물%추궁근라정%요추퇴변%골수니%골질소송
lumbar vertebra%internal fixators%osteoporosis%pain
背景:老年腰椎退变患者在手术中常面临椎弓根螺钉把持力不足情况,易发生脱钉、固定不牢靠等风险,如何增加螺钉的把持力成为研究的热点。目的:探讨使用椎弓根螺钉骨水泥强化方案治疗老年腰椎退变的早期临床效果。方法:选择2012年8月至2014年4月收治的患腰椎退行性疾病行腰椎内固定治疗的患者65例,根据修复方案分为2组,椎弓根螺钉内固定骨水泥强化组24例,常规椎弓根螺钉内固定组41例。比较两组患者的一般情况,采用目测类比评分法和日本矫形科学学会腰椎功能评分表对患者腰背疼痛及下肢神经功能恢复情况进行评估。结果与结论:65例患者均完成手术,获得随访,随访时间为3-20个月,随访中均行腰椎正侧位片X射线片,未发现螺钉松动、脱落、断裂、椎间隙高度丢失等情况。椎弓根螺钉内固定骨水泥强化组患者的手术出血量、住院时间与常规椎弓根螺钉内固定组差异无显著性意义(P>0.05),椎弓根螺钉内固定骨水泥强化组术后3,6个月日本矫形科学学会腰椎功能评分及术后3个月的目测类比评分均较常规椎弓根螺钉内固定组显著改善(P <0.05);两组术后6个月的目测类比评分差异无显著性意义(P >0.05)。提示将骨水泥沿椎弓根螺钉钉道注入椎弓根及椎体,可达到螺钉骨水泥强化的目的,增加螺钉的把持力,重建腰椎的稳定性,取得了满意的近期疗效。
揹景:老年腰椎退變患者在手術中常麵臨椎弓根螺釘把持力不足情況,易髮生脫釘、固定不牢靠等風險,如何增加螺釘的把持力成為研究的熱點。目的:探討使用椎弓根螺釘骨水泥彊化方案治療老年腰椎退變的早期臨床效果。方法:選擇2012年8月至2014年4月收治的患腰椎退行性疾病行腰椎內固定治療的患者65例,根據脩複方案分為2組,椎弓根螺釘內固定骨水泥彊化組24例,常規椎弓根螺釘內固定組41例。比較兩組患者的一般情況,採用目測類比評分法和日本矯形科學學會腰椎功能評分錶對患者腰揹疼痛及下肢神經功能恢複情況進行評估。結果與結論:65例患者均完成手術,穫得隨訪,隨訪時間為3-20箇月,隨訪中均行腰椎正側位片X射線片,未髮現螺釘鬆動、脫落、斷裂、椎間隙高度丟失等情況。椎弓根螺釘內固定骨水泥彊化組患者的手術齣血量、住院時間與常規椎弓根螺釘內固定組差異無顯著性意義(P>0.05),椎弓根螺釘內固定骨水泥彊化組術後3,6箇月日本矯形科學學會腰椎功能評分及術後3箇月的目測類比評分均較常規椎弓根螺釘內固定組顯著改善(P <0.05);兩組術後6箇月的目測類比評分差異無顯著性意義(P >0.05)。提示將骨水泥沿椎弓根螺釘釘道註入椎弓根及椎體,可達到螺釘骨水泥彊化的目的,增加螺釘的把持力,重建腰椎的穩定性,取得瞭滿意的近期療效。
배경:노년요추퇴변환자재수술중상면림추궁근라정파지력불족정황,역발생탈정、고정불뢰고등풍험,여하증가라정적파지력성위연구적열점。목적:탐토사용추궁근라정골수니강화방안치료노년요추퇴변적조기림상효과。방법:선택2012년8월지2014년4월수치적환요추퇴행성질병행요추내고정치료적환자65례,근거수복방안분위2조,추궁근라정내고정골수니강화조24례,상규추궁근라정내고정조41례。비교량조환자적일반정황,채용목측류비평분법화일본교형과학학회요추공능평분표대환자요배동통급하지신경공능회복정황진행평고。결과여결론:65례환자균완성수술,획득수방,수방시간위3-20개월,수방중균행요추정측위편X사선편,미발현라정송동、탈락、단렬、추간극고도주실등정황。추궁근라정내고정골수니강화조환자적수술출혈량、주원시간여상규추궁근라정내고정조차이무현저성의의(P>0.05),추궁근라정내고정골수니강화조술후3,6개월일본교형과학학회요추공능평분급술후3개월적목측류비평분균교상규추궁근라정내고정조현저개선(P <0.05);량조술후6개월적목측류비평분차이무현저성의의(P >0.05)。제시장골수니연추궁근라정정도주입추궁근급추체,가체도라정골수니강화적목적,증가라정적파지력,중건요추적은정성,취득료만의적근기료효。
BACKGROUND:Elderly patients with degenerative lumbar degeneration often appear insufficient holding power of pedicle screw in spine surgery, which is prone to occur de-pinning and leads to insecure fixation. How to increase the holding power of screws has become a hot research. OBJECTIVE:To observe the early clinical effect of pedicle screws with cement augmentation for treating lumbar degenerative diseases in elderly patients. METHODS:A total of 65 old patients with lumbar degenerative diseases received a treatment between August 2012 and April 2014, and were divided into two groups according to the treatment strategy:treatment group (n=24;internal fixation of pedicle screws with cement augmentation) and control group (n=41;routine internal fixation of pedicle screws). General conditions of patients in two groups were observed and compared. Visual analog scale (VAS) and Japanese Orthopaedic Association (JOA) score system were used for evaluating the lumbar and back pain, and restoration of neurological function in lower limbs respectively. RESULTS AND CONCLUSION:Al of the patients successful y received the surgery and then were fol owed up from 3 to 20 months. The anterioposterior and lateral X-ray film revealed no loosening, loss, fracture of the screws, and no loss of intervetebral space height was found. There was no significant difference in the blood loss and hospital stay between two groups (P>0.05). JOA at postoperative 3 and 6 months, and VAS score at postoperative 3 months were significantly improved after the treatment of pedicle screws with cement augmentation, when compared to control group (P<0.05). VAS scores showed no difference at 6 months postoperatively in two groups (P>0.05). Pedicle screws with cement augmentation for treating lumbar degenerative diseases have the advantages of improving the screws holding strength, reconstructing the stability of lumbar vertebra and obtaining clinical efficacy on degenerative spine.