妇产与遗传（电子版）
婦產與遺傳（電子版）
부산여유전（전자판）
Obstetrics-Gynecology and Genetics(Electronic Edition)
2014年
2期
41-43
,共3页
妊娠期妇女%假丝酵母菌病%菌种%药敏%疗效
妊娠期婦女%假絲酵母菌病%菌種%藥敏%療效
임신기부녀%가사효모균병%균충%약민%료효
Pregnant women%candidiasis%Bacteria%susceptibility%efficacy
目的：探讨妊娠期外阴阴道假丝酵母菌病（VVC）的菌种分布及相关研究，为临床诊治妊娠期VVC提供一定的理论依据。方法选取2012年2月至2012年4月在东莞市妇幼保健院门诊就诊的确诊有VVC的孕妇100例为研究组，确诊为非妊娠VVC的妇女100例为对照组，对入选病例阴道分泌物进行假丝酵母菌菌种的鉴定、药敏试验、临床疗效评价对比。结果妊娠期VVC和非妊娠期VVC在菌种的分布上无明显统计学差异（χ2=7.077，P=0.054），但两组VVC在非白假丝酵母菌的分布上显著不同（χ2=6.974，P=0.023）；白假丝酵母菌的对克霉唑敏感性明显高于非白假丝酵母菌（Z=-2.212，P=0.027）；感染白假丝酵母菌患者的单疗程治愈率明显高于感染非白假丝酵母菌的患者（χ2=12.978，P<0.001）。结论妊娠期和非妊娠期VVC菌种鉴定对妊娠期VVC的诊疗有实际的指导意义。
目的：探討妊娠期外陰陰道假絲酵母菌病（VVC）的菌種分佈及相關研究，為臨床診治妊娠期VVC提供一定的理論依據。方法選取2012年2月至2012年4月在東莞市婦幼保健院門診就診的確診有VVC的孕婦100例為研究組，確診為非妊娠VVC的婦女100例為對照組，對入選病例陰道分泌物進行假絲酵母菌菌種的鑒定、藥敏試驗、臨床療效評價對比。結果妊娠期VVC和非妊娠期VVC在菌種的分佈上無明顯統計學差異（χ2=7.077，P=0.054），但兩組VVC在非白假絲酵母菌的分佈上顯著不同（χ2=6.974，P=0.023）；白假絲酵母菌的對剋黴唑敏感性明顯高于非白假絲酵母菌（Z=-2.212，P=0.027）；感染白假絲酵母菌患者的單療程治愈率明顯高于感染非白假絲酵母菌的患者（χ2=12.978，P<0.001）。結論妊娠期和非妊娠期VVC菌種鑒定對妊娠期VVC的診療有實際的指導意義。
목적：탐토임신기외음음도가사효모균병（VVC）적균충분포급상관연구，위림상진치임신기VVC제공일정적이론의거。방법선취2012년2월지2012년4월재동완시부유보건원문진취진적학진유VVC적잉부100례위연구조，학진위비임신VVC적부녀100례위대조조，대입선병례음도분비물진행가사효모균균충적감정、약민시험、림상료효평개대비。결과임신기VVC화비임신기VVC재균충적분포상무명현통계학차이（χ2=7.077，P=0.054），단량조VVC재비백가사효모균적분포상현저불동（χ2=6.974，P=0.023）；백가사효모균적대극매서민감성명현고우비백가사효모균（Z=-2.212，P=0.027）；감염백가사효모균환자적단료정치유솔명현고우감염비백가사효모균적환자（χ2=12.978，P<0.001）。결론임신기화비임신기VVC균충감정대임신기VVC적진료유실제적지도의의。
Objective To discuss the species distribution of VVC during pregnancy, and to provide theoretical basis for clinical diagnosis and treatment. Method 200 cases from February 2012 to April 2012 in our hospital were selected divided into 2 groups: 100 cases of pregnant women diagnosed with VVC as the research group, 100 cases of non-pregnant women diagnosed with VVC as the control group. The vaginal secretions of two groups were conducted candidiasis species identification, susceptibility testing, clinical evaluation and compared. Results There was no significant difference in the distribution of species between pregnancy VVC and non-pregnancy VVC(χ2=7.077,P=0.054). there was significant difference in the distribution of non-albicans(χ2=6.974,P=0.023), Candida albicans was more sensitive to clotrimazole than non-albicans (Z=-2.212,P=0.027), patients infected with Candida albicanshad a higher cure rate than patients infected with non-albicans(χ2=12.978,P<0.001). Conclusions The species identification of VVC during pregnancy and VVC during non-pregnancy has practical guiding significance in the diagnosis and treatment.
