CAJ | 학술논문

活性氧既是细胞内的信号分子，也是引起细胞氧化应激的主要分子。适当强度的运动促进生理水平活性氧的生成，增强机体抗氧化能力，有助于改善代谢、延缓衰老及相关疾病；而过度运动则会导致机体内大量活性氧的产生，造成运动疲劳甚至运动损伤。线粒体是产生活性氧及维护细胞氧化还原稳态的主要细胞器。合理补充线粒体营养素可以维护细胞氧化还原稳态，部分模拟运动的生理效应；同时，能够缓解过度运动引起的运动疲劳，有助于提升运动能力并改善运动损伤。
활성양기시세포내적신호분자，야시인기세포양화응격적주요분자。괄당강도적운동촉진생리수평활성양적생성，증강궤체항양화능력，유조우개선대사、연완쇠로급상관질병；이과도운동칙회도치궤체내대량활성양적산생，조성운동피로심지운동손상。선립체시산생활성양급유호세포양화환원은태적주요세포기。합리보충선립체영양소가이유호세포양화환원은태，부분모의운동적생리효응；동시，능구완해과도운동인기적운동피로，유조우제승운동능력병개선운동손상。
ROS,identifiedassignalingmolecules,areresponsibleformaintainingredoxhomeostasisin vivo.Appropriate exercise promotes the generation of physiological ROS,enhances the antioxidative po-tential,promotes exercise performance,and improves metabolism,as well as retards aging and related diseases;whereas overload exercise causes excess ROS,resulting in exercise-induced fatigue or even ex-ercise-induced injury.Mitochondria are the main pool of ROS production and act as the key organelles in modulating intracellular redox homeostasis.Mitochondrial nutrients not only maintain physiological redox homeostasis,but also ameliorate oxidative stress and fatigue induced by overload exercise,eventually im-proving exercise performance and preventing/ameliorating exercise-induced injury.