CAJ | 학술논문

目的：探讨早产儿肺透明膜病（HMD）发病及影响预后的高危因素，为新生儿肺透明膜病发病提供预防措施。方法：选择67例HMD患儿为研究对象，同期住院的1194例早产儿为对照组，回顾性分析与HMD发病及预后有关的危险因素。结果：围生期窒息、前置胎盘、胎盘早剥、小胎龄、低体重为早产儿HMD发生的高危因素，而胎膜早破及产前使用糖皮质激素对HMD有预防作用。而胎龄越小、体重越低HMD预后越差，早期使用肺表面活性物质明显提高HMD存活率。结论：对孕母特别是高危妊娠孕母重视产前检查，及时发现问题并予以正确处理，减少早产，积极消除HMD高危因素，积极治疗，降低HMD的发病率及病死率。
목적：탐토조산인폐투명막병（HMD）발병급영향예후적고위인소，위신생인폐투명막병발병제공예방조시。방법：선택67례HMD환인위연구대상，동기주원적1194례조산인위대조조，회고성분석여HMD발병급예후유관적위험인소。결과：위생기질식、전치태반、태반조박、소태령、저체중위조산인HMD발생적고위인소，이태막조파급산전사용당피질격소대HMD유예방작용。이태령월소、체중월저HMD예후월차，조기사용폐표면활성물질명현제고HMD존활솔。결론：대잉모특별시고위임신잉모중시산전검사，급시발현문제병여이정학처리，감소조산，적겁소제HMD고위인소，적겁치료，강저HMD적발병솔급병사솔。
Objective: To discuss the high risk factors of pathogenesis and prognosis with hyaline membrane disease in premature infant, and to provide preventive measures for hyaline membrane disease in premature infant. Methods: 67 children who were confirmed hyaline membrane disease were chosen as the objects of the research, as the same time in the hospital,1194 premature infants were allocated into control groups, the high risk factors of pathogenesis and prognosis with HMD would be retrospective analysis. Results: Asphyxia in perinatal period, placenta previa, placental abruption, small gestational age, low-body weight was the high risk factors of the happening of HMD, but premature rupture of membranes and antenatal glucocorticoids were preventions for HMD. The smaller of the gestational age and the lower of the weight, the prognosis of HMD were the worse. In the early stage, using the pulmonary surfactants could improve the survival rates of HMD. Conclusion: Pregnant woman, especially high risk pregnant women should attach importance to prenatal examination, find problems in time and correctly dispose, eliminate the high risk factors of HMD, reduce the premature infants, treat actively, and reduce the morbidities and the case fatality rates of HMD.