CAJ | 학술논문

目的：研究正电子发射断层/计算机断层（PET/CT）显像中呼吸运动对肺阳性病灶标准摄取值（SUV）的影响及校正方法。方法：用模型模拟呼吸运动进行PET/CT显像，研究呼吸运动对阳性球状灶SUV的影响，提出数学校正方法，并通过临床病例分析进行验证。结果：与静止时PET图像比较，呼吸运动时采集的阳性球状灶SUV降低，但体积（VPET）相应增大，而其内的总放射性（TR=SUV平均×V）保持不变。临床上，PET所示病灶为呼吸运动叠加的结果，而高速多排螺旋CT所示的病灶体积（VCT）与真实体积比较接近，因此建立了通过公式SUV校正=(SUV测量×VPET)/VCT进行校正的方法。结论：PET/CT显像中肺结节的SUV因呼吸运动而被低估，可通过所建简便方法进行校正。
목적：연구정전자발사단층/계산궤단층（PET/CT）현상중호흡운동대폐양성병조표준섭취치（SUV）적영향급교정방법。방법：용모형모의호흡운동진행PET/CT현상，연구호흡운동대양성구상조SUV적영향，제출수학교정방법，병통과림상병례분석진행험증。결과：여정지시PET도상비교，호흡운동시채집적양성구상조SUV강저，단체적（VPET）상응증대，이기내적총방사성（TR=SUV평균×V）보지불변。림상상，PET소시병조위호흡운동첩가적결과，이고속다배라선CT소시적병조체적（VCT）여진실체적비교접근，인차건립료통과공식SUV교정=(SUV측량×VPET)/VCT진행교정적방법。결론：PET/CT현상중폐결절적SUV인호흡운동이피저고，가통과소건간편방법진행교정。
Objective: This study was designed to investigate the impact of breathing on evaluation of positive lung nodules and establish a correction method for positron emission tomography/computed tomography (PET/CT). Methods: Model studies are adopted to simulate breathing. Its influence on the standardized uptake value (SUV) of positive nodules on PET/CT images were analyzed by correlating with the images obtained in static status. A mathematic correction method was established and veriifed through case analysis. Results:Compared with the PET images under static status, the average SUVs under breathing status decreased, whereas the nodule volume (V) increased correspondingly and the total radioactivity (TR=SUVmean×V) remained the same. Because the volume measured on the high-speed multi-detector CT was relatively accurate, the decreased SUVs on clinical PET images with breathing inlfuence could be corrected using a formula: SUVcor ected= (SUVmeasured × VPET) /VCT. Conclusion:A mathematic method is preliminarily established to correct the breathing-related underestimation of the SUVs of positive lung nodules on PET/CT images.