化学研究
化學研究
화학연구
CHEMICAL RESEARCHES
2014年
5期
482-487
,共6页
苯并噻二唑%荧光化学传感器%氟离子%检测
苯併噻二唑%熒光化學傳感器%氟離子%檢測
분병새이서%형광화학전감기%불리자%검측
benzotiadiazole%fluorescent chemodosimeter%fluoride ion%detection
研制了一种用于灵敏、快速地检测溶液中的氟离子的基于苯并噻二唑衍生物的荧光传感器.4,7-二溴-2,1,3-苯并噻二唑与三甲基硅基乙炔通过 Sonogashira 偶联反应得到二取代的三甲基硅基乙炔苯并噻二唑;将该化合物用于检测氟离子,分析了检测灵敏度和选择性.结果表明,在乙腈和水(V/V =9∶1)混合溶液中,合成的苯并噻二唑衍生物的最大发射波长峰值为455 nm (激发波长为376 nm);就所测试的 F-,Cl-,Br-,I-, ClO 4-,AcO -,NO 3-,H 2 PO 3-,CN-和 HSO 4-等阴离子而言,仅 F-可以脱除三甲基硅保护基使得该化合物荧光最大发射波长蓝移至435 nm,荧光强度降低60%,且最低检测限可达4.5×10-8 mol/L.因此,二取代的三甲基硅基乙炔苯并噻二唑应用于氟离子检测具有很好的灵敏度和选择性.
研製瞭一種用于靈敏、快速地檢測溶液中的氟離子的基于苯併噻二唑衍生物的熒光傳感器.4,7-二溴-2,1,3-苯併噻二唑與三甲基硅基乙炔通過 Sonogashira 偶聯反應得到二取代的三甲基硅基乙炔苯併噻二唑;將該化閤物用于檢測氟離子,分析瞭檢測靈敏度和選擇性.結果錶明,在乙腈和水(V/V =9∶1)混閤溶液中,閤成的苯併噻二唑衍生物的最大髮射波長峰值為455 nm (激髮波長為376 nm);就所測試的 F-,Cl-,Br-,I-, ClO 4-,AcO -,NO 3-,H 2 PO 3-,CN-和 HSO 4-等陰離子而言,僅 F-可以脫除三甲基硅保護基使得該化閤物熒光最大髮射波長藍移至435 nm,熒光彊度降低60%,且最低檢測限可達4.5×10-8 mol/L.因此,二取代的三甲基硅基乙炔苯併噻二唑應用于氟離子檢測具有很好的靈敏度和選擇性.
연제료일충용우령민、쾌속지검측용액중적불리자적기우분병새이서연생물적형광전감기.4,7-이추-2,1,3-분병새이서여삼갑기규기을결통과 Sonogashira 우련반응득도이취대적삼갑기규기을결분병새이서;장해화합물용우검측불리자,분석료검측령민도화선택성.결과표명,재을정화수(V/V =9∶1)혼합용액중,합성적분병새이서연생물적최대발사파장봉치위455 nm (격발파장위376 nm);취소측시적 F-,Cl-,Br-,I-, ClO 4-,AcO -,NO 3-,H 2 PO 3-,CN-화 HSO 4-등음리자이언,부 F-가이탈제삼갑기규보호기사득해화합물형광최대발사파장람이지435 nm,형광강도강저60%,차최저검측한가체4.5×10-8 mol/L.인차,이취대적삼갑기규기을결분병새이서응용우불리자검측구유흔호적령민도화선택성.
A ratiometric fluorescent chemodosimeter based on benzotiadiazole derivative has been developed for detecting fluoride ion (F- )in solution sensitively and rapidly.Namely,bis-trimethylsilylalkyne benzothiadiazole was prepared by Sonogashira coupling reaction of 4,7-di-bromo-2,1,3-benzothiadiazole and trimethylsilyl ethyne.As-synthesized product was used to detect F- ,and the detection sensitivity and selectivity were analyzed.Results show that the e-mission band of the as-synthesized benzothiadiazole derivative in the mixture of acetonitrile and water (V/V = 9∶1)is centered around 455 nm (the excitation wavelength is 376 nm).Among tested anions such as F- , Cl- , Br- , I- , ClO 4 - , AcO - , NO 3 - , H 2 PO 3 - , CN- and HSO 4 - ,only F- is able to eliminate the trimethylsilyl (TMS)protective group thereby lead-ing to a blue shift of the maximum fluorescent emission wavelength from 455 nm to 435 nm as well as a decrease of the fluorescence intensity by 40%, with the detection 1imit being 4.5×10 -8 mol/L.This means that bis-trimethylsilylalkyne benzothiadiazole can be well used to detect F- with good sensitivity and selectivity.