CAJ | 학술논문

目的：探讨卒中后阻塞性睡眠呼吸暂停综合征患者相关危险因素，为临床诊断和防治提供理论依据。方法60名入组患者均登记相关危险因素、影像学检查，并行便携式多导睡眠监测，按照监测结果分为卒中合并OSAS组（CS-OSAS组）、脑卒中组（CS组）及OSAS组；并分析其影响因素。结果 OSAS发生率为58．3％；CS-OSAS组及OSAS组患者的AHI、ODI、SaO2＜90％的时间、夜间平均SaO2、夜间最低SaO2与CS组患者比较差异有统计学意义（ P＜0．05）；但CS-OSAS组及OSAS组之间比较无统计学意义（ P＞0．05）。 CS-OSAS组合并高血压的比例高于CS组及OSAHS组患者，差异有统计学意义（P＜0．05）。 CS-OSAS组及OSAS组患者吸烟、饮酒、BMI、高血压病、糖尿病比例均高于CS组（P＜0．05）。结论 CS-OSAS与OSAS患者存在明显的夜间低氧血症与呼吸暂停；吸烟、饮酒及BMI、高血压病、糖尿病可能是CS-OSAS发生的危险因素。
목적：탐토졸중후조새성수면호흡잠정종합정환자상관위험인소，위림상진단화방치제공이론의거。방법60명입조환자균등기상관위험인소、영상학검사，병행편휴식다도수면감측，안조감측결과분위졸중합병OSAS조（CS-OSAS조）、뇌졸중조（CS조）급OSAS조；병분석기영향인소。결과 OSAS발생솔위58．3％；CS-OSAS조급OSAS조환자적AHI、ODI、SaO2＜90％적시간、야간평균SaO2、야간최저SaO2여CS조환자비교차이유통계학의의（ P＜0．05）；단CS-OSAS조급OSAS조지간비교무통계학의의（ P＞0．05）。 CS-OSAS조합병고혈압적비례고우CS조급OSAHS조환자，차이유통계학의의（P＜0．05）。 CS-OSAS조급OSAS조환자흡연、음주、BMI、고혈압병、당뇨병비례균고우CS조（P＜0．05）。결론 CS-OSAS여OSAS환자존재명현적야간저양혈증여호흡잠정；흡연、음주급BMI、고혈압병、당뇨병가능시CS-OSAS발생적위험인소。
Objective To investigate related risk factors of patients with poststroke obstructive sleep apnea syndrome ( OS-AS) in order to provide basis for diagnosis and treatment .Methods 60 patients were studied .All the patients completed im-age examinations and their basic information and related risk factors were registered .They were divided into 3 groups based on polysomnography:the cerebral stroke combined with OSAS group (CS-OSAS group),cerebral stroke group(CS group)and OS-AS group.Clinical factors among the three groups were compared to identify the risk factors .Results The incidence of OSAS was 58.3%.Compared with CS group ,there was statistical differences in terms of AHI ,ODI and,mean SaO2 ,MinSaO2 <90%, MinSaO2 in CS-OSAS group and OSAS group(P<0.05),but no differences between CS-OSAS group and OSAS group.There was a higher rate of complicated hypertension in CS-OSAS group than in CS group and OSAS group .The difference was signifi-cant(P<0.05).In comparison with CS group,the rates of smoking,alcohol,BMI,hypertension and diabetes in CS-OSAS group and OSAS group were significantly higher (P<0.05).Conclusion Apparently, hypopnea and sleep apnea exist in patients with CO-OSAS and OSAS.The rates of smoking,alcohol,BMI,hypertension and diabetes are often regarded as predictors of CS-OSAS.