CAJ | 학술논문

目的：观察健脾消胀片对大鼠胆汁分泌的影响。方法：大鼠60只，分为6组，分别灌服健脾消胀片(大、中、小剂量)混悬液；舒胆通混悬液；清肝利胆胶囊混悬液和同体积的0.5%羧甲基纤维素；每天给药1次，连续给药5 d。收集各组大鼠胆汁量，检测胆汁中总胆汁酸、总胆固醇、总胆红素等含量。结果：健脾消胀片可使大鼠胆汁中胆汁酸、胆红素含量显著升高(P<0.01)，胆固醇含量显著降低(P<0.01)。结论：健脾消胀片有促进胆汁分泌的作用。
목적：관찰건비소창편대대서담즙분비적영향。방법：대서60지，분위6조，분별관복건비소창편(대、중、소제량)혼현액；서담통혼현액；청간리담효낭혼현액화동체적적0.5%최갑기섬유소；매천급약1차，련속급약5 d。수집각조대서담즙량，검측담즙중총담즙산、총담고순、총담홍소등함량。결과：건비소창편가사대서담즙중담즙산、담홍소함량현저승고(P<0.01)，담고순함량현저강저(P<0.01)。결론：건비소창편유촉진담즙분비적작용。
Objective:To observe the effect of Jianpi Xiaozhang tablets on the bile secretion in rats. Methods: Totally 60 rats were divided into 6 groups randomly. Jianpi Xiaozhang tablet suspension(high, moderate, low dosages), Shudantong suspension, Qinggan Lidan capsule suspension and 0. 5% carboxymethyl cellulose with the same volume was respectively given with intragastric ga-vage once daily for continuous 5 days. The bile was collected to detect total bile acids ( TBA) , total cholesterol and total bilirubin. Re-sults:Jianpi Xiaozhang tablets could notably increase TBA and total bilirubin in the bile (P<0. 01), and decrease the cholesterol content significantly (P<0. 01). Conclusion:Jianpi Xiaozhang tablets can promote the bile secretion.