现代诊断与治疗
現代診斷與治療
현대진단여치료
MODERN DIAGNOSIS AND TREATMENT
2014年
11期
2466-2467,2468
,共3页
刘周强%赵军%许光华
劉週彊%趙軍%許光華
류주강%조군%허광화
MicroRNA%肾癌%发病机制%诊断%治疗
MicroRNA%腎癌%髮病機製%診斷%治療
MicroRNA%신암%발병궤제%진단%치료
MicroRNA%Kidney cancer%Mechanism%Diagnosis%Therapy
MicroRNA(miRNA)是一类长度在18~25个核苷酸的内源性非编码单链小分子RNA,在转录后水平调控基因表达,影响细胞生长、增殖、分化和凋亡等生理或病理过程。肾癌是泌尿系统中一种非常常见的恶性肿瘤。研究表明, miRNA在肾癌的发生、发展过程中发挥了重要作用。本文就miRNA在肾癌中的研究进展予以综述。
MicroRNA(miRNA)是一類長度在18~25箇覈苷痠的內源性非編碼單鏈小分子RNA,在轉錄後水平調控基因錶達,影響細胞生長、增殖、分化和凋亡等生理或病理過程。腎癌是泌尿繫統中一種非常常見的噁性腫瘤。研究錶明, miRNA在腎癌的髮生、髮展過程中髮揮瞭重要作用。本文就miRNA在腎癌中的研究進展予以綜述。
MicroRNA(miRNA)시일류장도재18~25개핵감산적내원성비편마단련소분자RNA,재전록후수평조공기인표체,영향세포생장、증식、분화화조망등생리혹병리과정。신암시비뇨계통중일충비상상견적악성종류。연구표명, miRNA재신암적발생、발전과정중발휘료중요작용。본문취miRNA재신암중적연구진전여이종술。
MicroRNA (miRNA) is a kind of endogenous non coding single stranded small molecule with 18~25 nucleotides. It regulates gene expression at the posttranscriptional level and influences bio-logical or pathological progress including growth,proliferation,differentiation and apoptosis of cell. Re-nal cell carcinoma is a type of urinary cancer which happens commonly. It is reported that miRNA plays a vital role in the carcinogenesis and progression of renal cell carcinoma. The purpose of this re-view is to reveal the relationship of miRNA in renal cancer.