CAJ | 학술논문

目的：探讨门冬氨酸钾镁对急性心肌梗死合并心律失常患者血液黏附状态的影响。方法选取本院2012年1月~2013年12月收治的55例急性心肌梗死合并心律失常患者为研究对象，给予急性心肌梗死的对症治疗，在此基础上加用门冬氨酸钾镁，观察治疗前后sICAM-1、sVCAM-1水平的变化。结果治疗后sICAM-1、sVCAM-1水平较治疗前均明显降低，差异有统计学意义(P<0.05)；治疗过程中，5例(9.1%)出现注射痛，未见其他明显不良反应。结论门冬氨酸钾镁可改善急性心肌梗死合并心律失常患者的血液黏附状态，降低sICAM-1和sVCAM-1水平，值得临床推广应用。
목적：탐토문동안산갑미대급성심기경사합병심률실상환자혈액점부상태적영향。방법선취본원2012년1월~2013년12월수치적55례급성심기경사합병심률실상환자위연구대상，급여급성심기경사적대증치료，재차기출상가용문동안산갑미，관찰치료전후sICAM-1、sVCAM-1수평적변화。결과치료후sICAM-1、sVCAM-1수평교치료전균명현강저，차이유통계학의의(P<0.05)；치료과정중，5례(9.1%)출현주사통，미견기타명현불량반응。결론문동안산갑미가개선급성심기경사합병심률실상환자적혈액점부상태，강저sICAM-1화sVCAM-1수평，치득림상추엄응용。
Objective To explore the influence of potassium aspartate and magnesium aspartate on blood adhesion state in patients with acute myocardial infarction combined with arrhythmia. Methods 55 cases of patients with acute my ocardial infarction combined with arrhythmia in our hospital from January 2012 to December 2013 were selected as re search objects,all these patients were given by the symptomatic treatment of acute myocardial infarction,and were treat ed potassium aspartate and magnesium aspartate treated on this basis,the change of sICAM-1,sVCAM-1 before and af ter treatment was observed respectively. Results After treatment,the level of sICAM-1,sVCAM-1 was lower than that before treatment respectively,with statistical difference(P约0.05).Injection pain was 5 cases(9.1%)in the process of treat ment,other adverse reactions were not observed. Conclusion The potassium aspartate and magnesium aspartate can im prove the blood adhesion in patients with acute myocardial infarction combined with arrhythmia,reduce the levels of sICAM-1 and sVCAM-1,it is worthy of clinical promotion and application.