中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2014年
24期
80-82
,共3页
氯吡格雷%速效救心丸%急性冠状动脉综合征
氯吡格雷%速效救心汍%急性冠狀動脈綜閤徵
록필격뢰%속효구심환%급성관상동맥종합정
Clopidogrel%Suxiaojiuxinwan%Acute coronary syndrome
目的：观察氯吡格雷联合速效救心丸治疗急性冠状动脉综合征的临床效果，以探讨其临床适用性。方法选择2012年3月~2013年12月于本院就诊的88例急性冠状动脉综合征患者，简单随机分为试验组45例和对照组43例，对照组给予氯吡格雷治疗，试验组则采用氯吡格雷联合速效救心丸治疗。观察两组患者的治疗效果及血液流变学的改善情况。结果试验组患者的心电图治疗有效率为93.33%，对照组为76.74%，两组比较差异有统计学意义(χ2=4.8063，P=0.0284)。试验组患者的治疗有效率为95.56%，对照组为81.40%，两组比较差异有统计学意义(字2=4.3773，P=0.0364)。患者服药后均未出现明显出血等不良反应；试验组患者的全血黏度和血浆黏度的改善情况均优于对照组，差异均有统计学意义(P<0.05)，试验组患者的血小板黏附率与对照组相当，差异无统计学意义(P>0.05)。结论氯吡格雷联合速效救心丸治疗急性冠状动脉综合征更有效、安全，适合临床推广应用。
目的：觀察氯吡格雷聯閤速效救心汍治療急性冠狀動脈綜閤徵的臨床效果，以探討其臨床適用性。方法選擇2012年3月~2013年12月于本院就診的88例急性冠狀動脈綜閤徵患者，簡單隨機分為試驗組45例和對照組43例，對照組給予氯吡格雷治療，試驗組則採用氯吡格雷聯閤速效救心汍治療。觀察兩組患者的治療效果及血液流變學的改善情況。結果試驗組患者的心電圖治療有效率為93.33%，對照組為76.74%，兩組比較差異有統計學意義(χ2=4.8063，P=0.0284)。試驗組患者的治療有效率為95.56%，對照組為81.40%，兩組比較差異有統計學意義(字2=4.3773，P=0.0364)。患者服藥後均未齣現明顯齣血等不良反應；試驗組患者的全血黏度和血漿黏度的改善情況均優于對照組，差異均有統計學意義(P<0.05)，試驗組患者的血小闆黏附率與對照組相噹，差異無統計學意義(P>0.05)。結論氯吡格雷聯閤速效救心汍治療急性冠狀動脈綜閤徵更有效、安全，適閤臨床推廣應用。
목적：관찰록필격뢰연합속효구심환치료급성관상동맥종합정적림상효과，이탐토기림상괄용성。방법선택2012년3월~2013년12월우본원취진적88례급성관상동맥종합정환자，간단수궤분위시험조45례화대조조43례，대조조급여록필격뢰치료，시험조칙채용록필격뢰연합속효구심환치료。관찰량조환자적치료효과급혈액류변학적개선정황。결과시험조환자적심전도치료유효솔위93.33%，대조조위76.74%，량조비교차이유통계학의의(χ2=4.8063，P=0.0284)。시험조환자적치료유효솔위95.56%，대조조위81.40%，량조비교차이유통계학의의(자2=4.3773，P=0.0364)。환자복약후균미출현명현출혈등불량반응；시험조환자적전혈점도화혈장점도적개선정황균우우대조조，차이균유통계학의의(P<0.05)，시험조환자적혈소판점부솔여대조조상당，차이무통계학의의(P>0.05)。결론록필격뢰연합속효구심환치료급성관상동맥종합정경유효、안전，괄합림상추엄응용。
Objective To observe the clinical effect of clopidogrel combination with Suxiaojiuxinwan treatment of acute coronary,in order to explore the investigate the clinical applicability. Methods 88 patients with acute coronary syn-dromes treated in our hospital from March 2012 to December 2013 were selected,they were simple randomly divided into experimental group in 45 cases and the control group in 43 cases,the control group was given clopidogrel treat-ment,the experimental group was given clopidogrel combination with Suxiaojiuxinwan treatment.The treatment effects and the improvement of blood rheology of two groups were observed. Results The electrocardiogram (ECG) treatment ef-fective rate in experimental group was 93.33%,the control group was 76.74%,the difference was statistically significant between the two groups (字2=4.8063,P=0.0284).The treatment effective rate in experimental group was 95.56%,the con-trol group was 81.40%,the difference was statistically significant between the two groups (χ2=4.3773,P=0.0364).Patients with no obvious bleeding occurred after taking the drug adverse reactions,the experimental group patients in the im-provement of the whole blood viscosity and plasma viscosity were superior to control group patients,the differences were statistically significant (P<0.05),the patients with platelet adhesion rate in experimental group and the control group was almost,there was no statistically significant difference (P>0.05). Conclusion Clopidogrel combination with Suxiaojiuxin-wan treatment of acute coronary syndromes is more effective,safe,and suitable for clinical application.
