中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2014年
24期
55-56,59
,共3页
急性脑梗死%粉防己碱%胆红素
急性腦梗死%粉防己堿%膽紅素
급성뇌경사%분방기감%담홍소
Acute cerebral infarction%Tetrandrine%Bilirubin
目的：探讨粉防己碱对急性脑梗死患者血清胆红素水平的影响。方法将符合要求的140例急性脑梗死患者随机分为治疗组和对照组，每组70例。两组患者均给予常规治疗，如改善脑循环、抗血小板聚集、调脂、脑保护等，治疗组在此基础上加用粉防己碱片剂口服。治疗前后进行血清胆红素水平测定，并对神经功能缺损进行评分。结果治疗前两组血清胆红素含量差异无统计学意义(P>0.05)；治疗后两组血清胆红素水平均升高，治疗后第7天达到最高水平，治疗组治疗后7、14 d血清胆红素水平高于对照组，差异有统计学意义(P<0.05)。治疗后7、14 d治疗组神经功能缺损程度评分低于对照组，差异有统计学意义(P<0.05)。结论粉防己碱治疗急性脑梗死可升高患者的血清胆红素水平，减轻脑组织损伤和减少神经功能缺损。
目的：探討粉防己堿對急性腦梗死患者血清膽紅素水平的影響。方法將符閤要求的140例急性腦梗死患者隨機分為治療組和對照組，每組70例。兩組患者均給予常規治療，如改善腦循環、抗血小闆聚集、調脂、腦保護等，治療組在此基礎上加用粉防己堿片劑口服。治療前後進行血清膽紅素水平測定，併對神經功能缺損進行評分。結果治療前兩組血清膽紅素含量差異無統計學意義(P>0.05)；治療後兩組血清膽紅素水平均升高，治療後第7天達到最高水平，治療組治療後7、14 d血清膽紅素水平高于對照組，差異有統計學意義(P<0.05)。治療後7、14 d治療組神經功能缺損程度評分低于對照組，差異有統計學意義(P<0.05)。結論粉防己堿治療急性腦梗死可升高患者的血清膽紅素水平，減輕腦組織損傷和減少神經功能缺損。
목적：탐토분방기감대급성뇌경사환자혈청담홍소수평적영향。방법장부합요구적140례급성뇌경사환자수궤분위치료조화대조조，매조70례。량조환자균급여상규치료，여개선뇌순배、항혈소판취집、조지、뇌보호등，치료조재차기출상가용분방기감편제구복。치료전후진행혈청담홍소수평측정，병대신경공능결손진행평분。결과치료전량조혈청담홍소함량차이무통계학의의(P>0.05)；치료후량조혈청담홍소수평균승고，치료후제7천체도최고수평，치료조치료후7、14 d혈청담홍소수평고우대조조，차이유통계학의의(P<0.05)。치료후7、14 d치료조신경공능결손정도평분저우대조조，차이유통계학의의(P<0.05)。결론분방기감치료급성뇌경사가승고환자적혈청담홍소수평，감경뇌조직손상화감소신경공능결손。
Objective To investigate the influence of tetrandrine on serum bilirubin in patients with acute cerebral in-farction (ACI). Methods One hundred and forty patients with ACI meeting the criteria were evenly divided into treat-ment group and control group in random.Regular treatments like improvement of cerebral circulation,anti-platelet ag-gregation,lipid regulation,and cerebral protection,etc. were provided in the two groups.Tetrandrine tablet for oral admin-istration was added to the treatment group on the basis of regular treatment.The levels of serum bilirubin before and af-ter therapy were tested and neurologic impairment was scored in order to compare whether there were differences in the two groups. Results There was no significant difference in the content of serum bilirubin before treatment in the two groups (P>0.05).After therapy,the level of serum bilirubin in both groups increased,and reached the highest level in 7th day.The levels of serum bilirubin 7 and 14 days after therapy in the treatment group were both higher than those in the control group,with statistical differences (P<0.05).The scores of neurologic impairment 7 and 14 days after therapy in the treatment group were both lower than those in the control group,which displayed statistical significances (P<0.05). Conclusion In the treatment of ACI,tetrandrine can increase the level of serum bilirubin,relieve cerebral injury,and re-duce neurologic impairment.
