中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2014年
24期
7-12
,共6页
药品规格%临床单次给药剂量%一致性%适配性%药物剂型
藥品規格%臨床單次給藥劑量%一緻性%適配性%藥物劑型
약품규격%림상단차급약제량%일치성%괄배성%약물제형
Drug specifications%Clinical single dose%Consistency%Suitability%Drug dosage form
目的：基于临床处方用药信息数据，考察药品规格与其临床单次给药剂量的一致性及适配性状况，为医疗机构选择药品规格、制药企业设计药品规格、政府部门制订有关药品规格管理政策等提供实证参考。方法从广州医科大学附属第四医院的医院信息系统中随机抽取10 d的处方信息数据，排除部分不符合要求的用药记录后，以5533张处方、16357条用药记录及621个药品品规作为研究样本，并建立用药记录数据库，然后对药品规格与其临床单次给药剂量一致性及适配性的用药记录频次与所占比例等统计指标进行分析。结果在全部用药记录中，药品规格与其临床单次给药剂量之间不一致、与不适配的用药记录比率分别为38.6%和20.3%。结论目前中国市面上流通的药品，尤其是儿科药品，其规格在与临床单次给药剂量的适配性方面还有较大的提升空间，政府部门、药品生产企业、医院等相关机构应共同努力解决好这一问题。
目的：基于臨床處方用藥信息數據，攷察藥品規格與其臨床單次給藥劑量的一緻性及適配性狀況，為醫療機構選擇藥品規格、製藥企業設計藥品規格、政府部門製訂有關藥品規格管理政策等提供實證參攷。方法從廣州醫科大學附屬第四醫院的醫院信息繫統中隨機抽取10 d的處方信息數據，排除部分不符閤要求的用藥記錄後，以5533張處方、16357條用藥記錄及621箇藥品品規作為研究樣本，併建立用藥記錄數據庫，然後對藥品規格與其臨床單次給藥劑量一緻性及適配性的用藥記錄頻次與所佔比例等統計指標進行分析。結果在全部用藥記錄中，藥品規格與其臨床單次給藥劑量之間不一緻、與不適配的用藥記錄比率分彆為38.6%和20.3%。結論目前中國市麵上流通的藥品，尤其是兒科藥品，其規格在與臨床單次給藥劑量的適配性方麵還有較大的提升空間，政府部門、藥品生產企業、醫院等相關機構應共同努力解決好這一問題。
목적：기우림상처방용약신식수거，고찰약품규격여기림상단차급약제량적일치성급괄배성상황，위의료궤구선택약품규격、제약기업설계약품규격、정부부문제정유관약품규격관리정책등제공실증삼고。방법종엄주의과대학부속제사의원적의원신식계통중수궤추취10 d적처방신식수거，배제부분불부합요구적용약기록후，이5533장처방、16357조용약기록급621개약품품규작위연구양본，병건립용약기록수거고，연후대약품규격여기림상단차급약제량일치성급괄배성적용약기록빈차여소점비례등통계지표진행분석。결과재전부용약기록중，약품규격여기림상단차급약제량지간불일치、여불괄배적용약기록비솔분별위38.6%화20.3%。결론목전중국시면상류통적약품，우기시인과약품，기규격재여림상단차급약제량적괄배성방면환유교대적제승공간，정부부문、약품생산기업、의원등상관궤구응공동노력해결호저일문제。
Objective To provide the empirical references for medical institutions selecting drug specifications,pharma-ceutical enterprises designing drug specifications,and government departments formulating relevant drug specifications management policies through surveying the consistency and suitability between drug specifications and its clinical sin-gle doses based on the clinical prescription information data. Methods The prescription information data of 10 days were randomly selected from the hospital information system of the Fourth Affiliated Hospital of Guangzhou Medical University,after excluding some drug-using records which did not conform to the requirements,the 5533 prescriptions, 16 357 drug-using records and 621 drugs were treated as the research sample,and a database was established,then the statistical indicators such as the frequencies and percentages of drug-using records of consistency and suitability be-tween drug specifications and its clinical single doses were analyzed. Results The inconsistency rate and unsuitability rate between drug specifications and its clinical single doses of total drug-using records were 38.6% and 20.3%,re-spectively. Conclusion As for the drugs,especially the pediatric drugs currently circulating on the market in our coun-try,the suitability between their specifications and clinical single doses has a large improvement space.The related orga-nizations,such as government departments,pharmaceutical enterprises,hospitals and so on,should make joint efforts to solve the problem.
