CAJ | 학술논문

研究了以苯甲酰氯和间苯二酚为原料、液碱为除酸剂，酯化合成然后精制得间苯二酚单苯甲酸酯的工艺．研究了酯化反应中温度、物料配比、pH、间苯二酚水溶液的浓度和反应时间等条件对反应的影响，获得了较佳的酯化工艺条件：苯甲酰氯与间苯二酚的摩尔比为1．15∶1；pH值为7．5；反应温度为25℃；反应时间为1．5 h；间苯二酚溶液的质量分数为10％．酯化反应收率为88．6％．考察了结晶溶剂配比、温度对产品质量和收率的影响，经实验评估得到了较佳的结晶工艺条件：结晶溶剂甲苯的体积（/mL）与初产物的质量（/g）之比为2．5∶1，结晶温度为30℃，结晶收率为95．0％．优化工艺条件下产品的总收率为84．2％．
연구료이분갑선록화간분이분위원료、액감위제산제，지화합성연후정제득간분이분단분갑산지적공예．연구료지화반응중온도、물료배비、pH、간분이분수용액적농도화반응시간등조건대반응적영향，획득료교가적지화공예조건：분갑선록여간분이분적마이비위1．15∶1；pH치위7．5；반응온도위25℃；반응시간위1．5 h；간분이분용액적질량분수위10％．지화반응수솔위88．6％．고찰료결정용제배비、온도대산품질량화수솔적영향，경실험평고득도료교가적결정공예조건：결정용제갑분적체적（/mL）여초산물적질량（/g）지비위2．5∶1，결정온도위30℃，결정수솔위95．0％．우화공예조건하산품적총수솔위84．2％．
A new process for preparation of resorcinol monobenzoate starting from benzoyl chloride and resor -cinol by esterification, extraction and crystallization was studied .The influence of temperature , pH, reaction time, resorcinol solution concentration and molar ratio of reactants on the yield of esterification was investiga -ted.The optimum reaction conditions were evaluated and selected as follows:the molar ratio of benzoyl chlo-ride to resorcinol was 1.15∶1, the pH value was 7.5, reaction temperature was 25 ℃, reaction time was 1.5 h, resorcinol solution concentration was 10%, under the optimum condition the yield of esters was about 88 .6%.The dosage of crystallization solvent and the temperature of crystallization were experimented also . The results of the experiments showed that the temperature of crystallization was 30 ℃.The ratio of solvent and reaction product was 2 .5∶1 .The yield of esterification product was about 95 .0%.The total yield was 84 .2%.