浙江师范大学学报（自然科学版）
浙江師範大學學報（自然科學版）
절강사범대학학보（자연과학판）
JOURNAL OF ZHEJIANG NORMAL UNIVERSITY(NATURAL SCIENCES)
2014年
3期
312-316
,共5页
2-芳基-4-戊烯基酯%α-芳基乙酰基苯并三唑%烯丙基碳酸乙酯%Tsuji-Trost反应%钯%一锅法
2-芳基-4-戊烯基酯%α-芳基乙酰基苯併三唑%烯丙基碳痠乙酯%Tsuji-Trost反應%鈀%一鍋法
2-방기-4-무희기지%α-방기을선기분병삼서%희병기탄산을지%Tsuji-Trost반응%파%일과법
2-aryl-4-pentenoates%α-aryl N-acetylbenzotriazoles%allyl ethyl carbonate%Tsuji-Trost reaction%palladium%one-pot
以α-芳基乙酰基苯并三唑和烯丙基碳酸乙酯为原料，Tsuji-Trost反应为关键步骤，通过“一锅法”操作合成了2-芳基-4-戊烯基酯，产率最高达85％。考察了催化剂、配体、溶剂等对反应的影响，确定了优化反应条件，并给出了可能的反应机理。产物经1 H NMR和13 C NMR分析确证。
以α-芳基乙酰基苯併三唑和烯丙基碳痠乙酯為原料，Tsuji-Trost反應為關鍵步驟，通過“一鍋法”操作閤成瞭2-芳基-4-戊烯基酯，產率最高達85％。攷察瞭催化劑、配體、溶劑等對反應的影響，確定瞭優化反應條件，併給齣瞭可能的反應機理。產物經1 H NMR和13 C NMR分析確證。
이α-방기을선기분병삼서화희병기탄산을지위원료，Tsuji-Trost반응위관건보취，통과“일과법”조작합성료2-방기-4-무희기지，산솔최고체85％。고찰료최화제、배체、용제등대반응적영향，학정료우화반응조건，병급출료가능적반응궤리。산물경1 H NMR화13 C NMR분석학증。
A one-pot synthesis of 2-aryl-4-pentenoates was realized by the Pd-catalyzed coupling of α-aryl N-acetylbenzotriazoles with allyl ethyl carbonate , followed by esterification reaction in alcohol solvents , produced yields up to 85%.The effects of catalyst , ligand and solvent on the yield were investigated .The optimum re-action conditions were determined and the possible mechanism was proposed .The products were identified by 1 H NMR and 13 C NMR.The present methodology provided several advantages such as mild reaction condition , excellent yield and environmental friendliness .
