CAJ | 학술논문

长期给予维生素 K 拮抗剂抗凝治疗的患者在行外科手术或行有创性操作时面临着出血风险，而在围术期停用维生素 K 拮抗剂又可能增加血栓栓塞风险。使用治疗剂量肝素类药物的桥接抗凝治疗后可避免围术期暂时中断维生素 K 拮抗剂治疗所致的血栓栓塞事件。本文对此进行有关讨论。
장기급여유생소 K 길항제항응치료적환자재행외과수술혹행유창성조작시면림착출혈풍험，이재위술기정용유생소 K 길항제우가능증가혈전전새풍험。사용치료제량간소류약물적교접항응치료후가피면위술기잠시중단유생소 K 길항제치료소치적혈전전새사건。본문대차진행유관토론。
Patients receiving long-term anticoagulation therapy of vitamin K antagonist (VKA)may face risk of bleeding when receive surgery or invasive operation,and perioperative interruption of VKA may increase risk of thromboembolism.Bridging anticoagulation therapy with therapeutic dose of heparin group drugs may avoid throm-boembolic events induced by temporary interruption of VKA therapy during perioperative period.This article made a relative discussion.